Multiphasic disseminated encephalomyelitis followed by optic neuritis in a child with gluten sensitivity

被引:4
作者
Ching, B. H. [1 ]
Mohamed, A. R. [1 ]
Khoo, T. B. [1 ]
Ismail, H. I. H. M. [1 ]
机构
[1] Hosp Kuala Lumpur, Dept Paediat, Paediat Neurol Unit, Kuala Lumpur 50586, Malaysia
关键词
Multiphasic disseminated encephalomyelitis; optic neuritis; gluten sensitivity; DEMYELINATION;
D O I
10.1177/1352458515593404
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Multiphasic disseminated encephalomyelitis (MDEM) followed by optic neuritis (ON) has been described as a new entity in recent years. Gluten encephalopathy has also been recognized as a neurological manifestation of celiac disease. Accurate diagnosis of both is important due to the therapeutic implications. We report a girl presenting with recurrent encephalopathic polyfocal demyelinating episodes followed by optic neuritis, and a clinical history suggestive of gluten sensitivity. She had persistently high ESR, neutrophilia, and tested positive for anti-MOG (myelin oligodendrocyte glycoprotein) antibody. She responded well to methylprednisolone in each relapse, and achieved remission for a year after azathioprine was added.
引用
收藏
页码:1209 / 1211
页数:3
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