Giant basal cell carcinoma of the skin: literature review and personal experience

被引:38
作者
Zoccali, G. [1 ]
Pajand, R. [1 ]
Papa, P. [1 ]
Orsini, G. [1 ]
Lomartire, N. [1 ]
Giuliani, M. [1 ]
机构
[1] Univ LAquila, Plast & Reconstruct Surg Sect, Dept Hlth Sci, Fac Med & Surg, Laquila, Italy
关键词
OF-THE-LITERATURE; MOHS MICROGRAPHIC SURGERY; SALIVARY-GLANDS; BASOSQUAMOUS CARCINOMA; SPONTANEOUS REGRESSION; PHOTODYNAMIC THERAPY; SURGICAL-MANAGEMENT; NECK RECONSTRUCTION; INCOMPLETE EXCISION; LOWER-EXTREMITY;
D O I
10.1111/j.1468-3083.2011.04427.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
As the most common form of skin cancer, basal cell carcinoma (BCC) is typified by locally infiltrative growth and a very low risk of metastasis. On occasion, however, this otherwise indolent neoplasm may behave aggressively, demonstrating deep tissue invasion and a high rate of postsurgical recurrence. The pathogenesis and determinants of such tenacious growth are not completely understood. Only 1% of all BCCs achieve the status of giant, as defined in 1988 by the American Joint Committee on Cancer. In this article, the authors provide a comprehensive review of the scientific literature on giant basal cell carcinoma (GBCC) of the skin and report their experience with this rare tumour subtype.
引用
收藏
页码:942 / 952
页数:11
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