Automated production and quality testing of [18F]labeled radiotracers using the BG75 system

被引：7

作者：

Anzellotti, Atilio ^{[1
]}

Bailey, Jim ^{[1
]}

Ferguson, Doug ^{[1
]}

McFarland, Aaron ^{[1
]}

Bochev, Pavel ^{[2
]}

Andreev, Georgiy ^{[3
]}

Awasthi, Vibhudutta ^{[4
]}

Brown-Proctor, Clive ^{[1
]}

机构：

[1] ABT Mol Imaging Inc, R&D, Louisville, TN 37777 USA

[2] Sveta Marina Univ Hosp, Nucl Med Unit, Varna, Bulgaria

[3] Int Inst Biol Syst, Diagnost Treatment Ctr, St Petersburg 197758, Russia

[4] Univ Oklahoma, Hlth Sci Ctr, Dept Pharmaceut Sci, Oklahoma City, OK 73117 USA

来源：

JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY | 2015年 / 305卷 / 02期

关键词：

PET; F-18; Automation; FDG; NaF; FMISO; F-18;

D O I：

10.1007/s10967-015-4045-1

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The simplification and automation of clinical PET radiotracer production, from isotope production to quality control, can streamline the current manufacturing workflow and, at the same time minimize the investment needed. In this article we present pre-clinical and clinical results showing the feasibility for manufacture of [F-18]fluoride labeled radiotracers such as [F-18]FDG, [F-18]NaF and [F-18]FMISO under automated conditions using the BG75 system.

引用

页码：387 / 401

页数：15

共 50 条

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