Photo catalogue for the classification of foci in the BALB/c 3T3 cell transformation assay

被引：32

作者：

Sasaki, Kiyoshi ^{[1
]}

Bohnenberger, Susanne ^{[2
]}

Hayashi, Kumiko ^{[1
]}

Kunkelmann, Thorsten ^{[2
]}

Muramatsu, Dai ^{[1
]}

Poth, Albrecht ^{[2
]}

Sakai, Ayako ^{[1
]}

Salovaara, Susan ^{[3
]}

Tanaka, Noriho ^{[1
]}

Thomas, B. Claire ^{[3
]}

Umeda, Makoto ^{[1
]}

机构：

[1] FDSC, HRI, Hadano, Kanagawa 2578523, Japan

[2] Harlan Cytotest Cell Res Harlan CCR GmbH, D-64380 Rossdorf, Germany

[3] Commiss European Communities, Joint Res Ctr, Inst Hlth & Consumer Protect, European Ctr Validat Alternat Methods, I-21027 Ispra, VA, Italy

来源：

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS | 2012年 / 744卷 / 01期

关键词：

Cell transformation assay; BALB/c 3T3 cell line; Carcinogenicity; Transformed foci; Photo catalogue; CELL-TRANSFORMATION; CHEMICALS;

D O I：

10.1016/j.mrgentox.2012.01.009

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

This catalogue is a display of focus photos representative of the BALB/c 3T3 cell transformation assay (CTA). It is intended as a visual aid for the identification and the scoring of foci in the conduct of the assay. A proper training from experienced personnel together with the protocol reported in this issue and the present photo catalogue will support method transfer and consistency in the assay results. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：42 / 53

页数：12

共 5 条

[1] QUANTITATIVE SYSTEM FOR ASSAY OF MALIGNANT TRANSFORMATION BY CHEMICAL CARCINOGENS USING A CLONE DERIVED FROM BALB/3T3 [J].