Direct oxidation of N-benzylamides to aldehydes or ketones by N-bromosuccinimide

被引：6

作者：

Wang, Guangjun ^{[2
,3
]}

Li, Zhengwei ^{[1
]}

Ha, Chengyong ^{[2
]}

Ding, Ke ^{[1
]}

机构：

[1] Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Guangzhou 510663, Guangdong, Peoples R China

[2] Chinese Acad Sci, Guangzhou Inst Chem, Key Lab Cellulose & Lignocellulosics Chem, Guangzhou 510663, Guangdong, Peoples R China

[3] Chinese Acad Sci, Grad Sch, Beijing, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2008年 / 38卷 / 10期

关键词：

aldehyde; amide; N-bromosuccinimide; ketone; oxidation;

D O I：

10.1080/00397910801929697

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and efficient approach for the one-pot transformation of N-benzylamides to aldehydes or ketones under mild conditions was reported. All the 20 substrates gave moderate to excellent oxidative yields under the optimized conditions. Our study may provide a new approach for the one-pot synthesis of aldehydes or ketones from the corresponding amides.

引用

页码：1629 / 1637

页数：9

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