A decade of progress in tissue engineering

被引：553
作者：
Khademhosseini, Ali [1 ,2 ,3 ,4 ,5 ]
Langer, Robert [2 ,6 ,7 ,8 ,9 ]
机构：
[1] Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Div Biomed Engn,Biomat Innovat Res Ctr, Cambridge, MA 02115 USA
[2] Harvard Mit Div Hlth Sci & Technol, Cambridge, MA 02139 USA
[3] Harvard Univ, Wyss Inst Biol Inspired Engn, Boston, MA 02115 USA
[4] Konkuk Univ, Coll Anim Biosci & Technol, Dept Bioind Technol, Seoul, South Korea
[5] King Abdulaziz Univ, Dept Phys, Jeddah, Saudi Arabia
[6] MIT, David H Koch Inst Integrat Canc Res, 77 Massachusetts Ave, Cambridge, MA 02139 USA
[7] Boston Childrens Hosp, Dept Anesthesiol, Boston, MA 02115 USA
[8] MIT, Dept Chem Engn, Cambridge, MA 02139 USA
[9] MIT, Inst Med Engn & Sci, 77 Massachusetts Ave, Cambridge, MA 02139 USA
来源：
NATURE PROTOCOLS | 2016年 / 11卷 / 10期
关键词：
STEM-CELL LINES; ORTHOTOPIC TRANSPLANTATION; MACROPHAGE ACTIVATION; DECELLULARIZED MATRIX; CONTROLLED-RELEASE; BLOOD-VESSELS; ORGANS; HYDROGELS; FABRICATION; VASCULARIZATION;
D O I：
10.1038/nprot.2016.123
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Tremendous progress has been achieved in the field of tissue engineering in the past decade. Several major challenges laid down 10 years ago, have been studied, including renewable cell sources, biomaterials with tunable properties, mitigation of host responses, and vascularization. Here we review advancements in these areas and envision directions of further development.
引用
收藏
页码：1775 / 1781
页数：7
相关论文
共 114 条
[1]   Engineering of blood vessels from acellular collagen matrices coated with human endothelial cells [J].
Amiel, Gilad E. ;
Komura, Makoto ;
Shapira, Oz ;
Yoo, James J. ;
Yazdani, Saami ;
Berry, Joel ;
Kaushal, Sunjay ;
Bischoff, Joyce ;
Atala, Anthony ;
Soker, Shay .
TISSUE ENGINEERING, 2006, 12 (08) :2355-2365
[2]   Foreign body reaction to biomaterials [J].
Anderson, James M. ;
Rodriguez, Analiz ;
Chang, David T. .
SEMINARS IN IMMUNOLOGY, 2008, 20 (02) :86-100
[3]  
[Anonymous], 2015, NATURE
[4]   Decellularization for whole organ bioengineering [J].
Arenas-Herrera, J. E. ;
Ko, I. K. ;
Atala, A. ;
Yoo, J. J. .
BIOMEDICAL MATERIALS, 2013, 8 (01)
[5]   Tissue-engineered autologous bladders for patients needing cystoplasty [J].
Atala, A ;
Bauer, SB ;
Soker, S ;
Yoo, JJ ;
Retik, AB .
LANCET, 2006, 367 (9518) :1241-1246
[6]   Bioorthogonal Click Chemistry: An Indispensable Tool to Create Multifaceted Cell Culture Scaffolds [J].
Azagarsamy, Malar A. ;
Anseth, Kristi S. .
ACS MACRO LETTERS, 2013, 2 (01) :5-9
[7]   The extracellular matrix as a scaffold for tissue reconstruction [J].
Badylak, SE .
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2002, 13 (05) :377-383
[8]   Whole-Organ Tissue Engineering: Decellularization and Recellularization of Three-Dimensional Matrix Scaffolds [J].
Badylak, Stephen F. ;
Taylor, Doris ;
Uygun, Korkut .
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 13, 2011, 13 :27-53
[9]   The Use of Whole Organ Decellularization for the Generation of a Vascularized Liver Organoid [J].
Baptista, Pedro M. ;
Siddiqui, Mohummad M. ;
Lozier, Genevieve ;
Rodriguez, Sergio R. ;
Atala, Anthony ;
Soker, Shay .
HEPATOLOGY, 2011, 53 (02) :604-617
[10]   Hydrogel bioprinted microchannel networks for vascularization of tissue engineering constructs [J].
Bertassoni, Luiz E. ;
Cecconi, Martina ;
Manoharan, Vijayan ;
Nikkhah, Mehdi ;
Hjortnaes, Jesper ;
Cristino, Ana Luiza ;
Barabaschi, Giada ;
Demarchi, Danilo ;
Dokmeci, Mehmet R. ;
Yang, Yunzhi ;
Khademhosseini, Ali .
LAB ON A CHIP, 2014, 14 (13) :2202-2211
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