The Holy Grail of LVAD-induced reversal of severe chronic heart failure: the need for integration

被引:6
作者
Yacoub, Magdi H. [1 ]
Terracciano, Cesare M. [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Natl Heart & Lung Inst, Harefield Heart Sci Ctr, Harefield UB9 6JH, Middx, England
关键词
VENTRICULAR ASSIST DEVICE; DILATED CARDIOMYOPATHY; RECOVERY; BRIDGE; CLENBUTEROL; THERAPY; CALCIUM;
D O I
10.1093/eurheartj/ehq503
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1052 / 1054
页数:3
相关论文
共 16 条
  • [11] Prolonged mechanical unloading reduces myofilament sensitivity to calcium and sarcoplasmic reticulum calcium uptake leading to contractile dysfunction
    Soppa, Gopal K. R.
    Lee, Joon
    Stagg, Mark A.
    Siedlecka, Urszula
    Youssef, Samuel
    Yacoub, Magdi H.
    Terracciano, Cesare. M. N.
    [J]. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2008, 27 (08) : 882 - 889
  • [12] Left ventricular assist device-induced molecular changes in the failing myocardium
    Soppa, Gopal K. R.
    Barton, Paul J. R.
    Terracciano, Cesare M. N.
    Yacoub, Magdi H.
    [J]. CURRENT OPINION IN CARDIOLOGY, 2008, 23 (03) : 206 - 218
  • [13] Role and possible mechanisms of clenbuterol in enhancing reverse remodelling during mechanical unloading in murine heart failure
    Soppa, Gopal K. R.
    Lee, Joon
    Stagg, Mark A.
    Felkin, Leanne E.
    Barton, Paul J. R.
    Siedlecka, Urszula
    Youssef, Samuel
    Yacoub, Magdi H.
    Terracciano, Cesare M. N.
    [J]. CARDIOVASCULAR RESEARCH, 2008, 77 (04) : 695 - 706
  • [14] Clinical recovery from end-stage heart failure using left-ventricular assist device and pharmacological therapy correlates with increased sarcoplasmic reticulum calcium content but not with regression of cellular hypertrophy
    Terracciano, CMN
    Hardy, J
    Birks, EJ
    Khaghani, A
    Banner, NR
    Yacoub, MH
    [J]. CIRCULATION, 2004, 109 (19) : 2263 - 2265
  • [15] Scarring in the heart - A reversible phenomenon?
    Towbin, Jeffrey A.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (17) : 1767 - 1768
  • [16] A novel strategy to maximize the efficacy of left ventricular assist devices as a bridge to recovery
    Yacoub, MH
    [J]. EUROPEAN HEART JOURNAL, 2001, 22 (07) : 534 - 540