Factorial clinical trials: a new approach to phase II neuro-oncology studies

被引：3

作者：

Iwamoto, Fabio M. ^{[1
,2
]}

Lassman, Andrew B. ^{[1
,2
]}

机构：

[1] Columbia Univ, Med Ctr, Dept Neurol, New York, NY 10027 USA

[2] Columbia Univ, Med Ctr, Herbert Irving Comprehens Canc Ctr, New York, NY 10027 USA

来源：

NEURO-ONCOLOGY | 2015年 / 17卷 / 02期

关键词：

NEWLY-DIAGNOSED GLIOBLASTOMA; TEMOZOLOMIDE; BEVACIZUMAB; DESIGN;

D O I：

10.1093/neuonc/nou314

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：174 / 176

页数：3

共 14 条

[1]

Abrams JS, 2014, NCI CLIN TRIALS REPO

[2]

Chinot OL, 2014, NEW ENGL J MED, V370, P709, DOI 10.1056/NEJMoa1308345

[3]

Dickersin K., 1993, ONLINE J CURR CLIN T

[4] Testing for the Presence of Positive-Outcome Bias in Peer Review A Randomized Controlled Trial [J].

Emerson, Gwendolyn B. ;

Warme, Winston J. ;

Wolf, Fredric M. ;

Heckman, James D. ;

Brand, Richard A. ;

Leopold, Seth S. .

ARCHIVES OF INTERNAL MEDICINE, 2010, 170 (21) :1934-1939

[5]

Fisher R. A., 1992, J MINISTRY AGR GREAT, P82, DOI DOI 10.1007/978-1-4612-4380-9_8

[6] A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma [J].

Gilbert, Mark R. ;

Dignam, James J. ;

Armstrong, Terri S. ;

Wefel, Jeffrey S. ;

Blumenthal, Deborah T. ;

Vogelbaum, Michael A. ;

Colman, Howard ;

Chakravarti, Arnab ;

Pugh, Stephanie ;

Won, Minhee ;

Jeraj, Robert ;

Brown, Paul D. ;

Jaeckle, Kurt A. ;

Schiff, David ;

Stieber, Volker W. ;

Brachman, David G. ;

Werner-Wasik, Maria ;

Tremont-Lukats, Ivo W. ;

Sulman, Erik P. ;

Aldape, Kenneth D. ;

Curran, Walter J., Jr. ;

Mehta, Minesh P. .

NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (08) :699-708

[7] A phase I factorial design study of dose-dense temozolomide alone and in combination with thalidomide, isotretinoin, and/or celecoxib as postchemoradiation adjuvant therapy for newly diagnosed glioblastoma [J].

Gilbert, Mark R. ;

Gonzalez, Javier ;

Hunter, Kathy ;

Hess, Kenneth ;

Giglio, Pierre ;

Chang, Eric ;

Puduvalli, Vinay ;

Groves, Morris D. ;

Colman, Howard ;

Conrad, Charles ;

Levin, Victor ;

Woo, Shaio ;

Mahajan, Anita ;

de Groot, John ;

Yung, W. K. Alfred .

NEURO-ONCOLOGY, 2010, 12 (11) :1167-1172

[8] Factorial design considerations [J].

Green, S ;

Liu, PY ;

O'Sullivan, J .

JOURNAL OF CLINICAL ONCOLOGY, 2002, 20 (16) :3424-3430

[9] CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2006-2010 [J].

Ostrom, Quinn T. ;

Gittleman, Haley ;

Farah, Paul ;

Ondracek, Annie ;

Chen, Yanwen ;

Wolinsky, Yingli ;

Stroup, Nancy E. ;

Kruchko, Carol ;

Barnholtz-Sloan, Jill S. .

NEURO-ONCOLOGY, 2013, 15 :1-56

[10] Randomized phase II adjuvant factorial study of dose-dense temozolomide alone and in combination with isotretinoin, celecoxib, and/or thalidomide for glioblastoma [J].

Penas-Prado, Marta ;

Hess, Kenneth R. ;

Fisch, Michael J. ;

Lagrone, Lore W. ;

Groves, Morris D. ;

Levin, Victor A. ;

De Groot, John F. ;

Puduvalli, Vinay K. ;

Colman, Howard ;

Volas-Redd, Gena ;

Giglio, Pierre ;

Conrad, Charles A. ;

Salacz, Michael E. ;

Floyd, Justin D. ;

Loghin, Monica E. ;

Hsu, Sigmund H. ;

Gonzalez, Javier ;

Chang, Eric L. ;

Woo, Shiao Y. ;

Mahajan, Anita ;

Aldape, Kenneth D. ;

Yung, W. K. Alfred ;

Gilbert, Mark R. .

NEURO-ONCOLOGY, 2015, 17 (02) :266-273

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