Evolving management of positive regional lymph nodes in melanoma: Past, present and future directions

被引：16

作者：

Fayne, Rachel A. ^{[1
]}

Macedo, Francisco, I ^{[2
]}

Rodgers, Steven E. ^{[1
]}

Moller, Mecker G. ^{[1
]}

机构：

[1] Univ Miami, Miller Sch Med, Sylvester Comprehens Canc Ctr, Div Surg Oncol,Dewitt Daughtry Dept Surg, Coral Gables, FL 33136 USA

[2] Univ Cent Florida, Coll Med, North Florida Reg Med Ctr, Dept Surg, Miami, FL USA

来源：

ONCOLOGY REVIEWS | 2019年 / 13卷 / 02期

关键词：

Melanoma; sentinel lymph node biopsy; completion lymph node dissection; AMERICAN JOINT COMMITTEE; HIGH-DOSE INTERFERON-ALPHA-2B; HIGH-RISK MELANOMA; SENTINEL-NODE; COMPLETION LYMPHADENECTOMY; METASTATIC MELANOMA; ADJUVANT IRRADIATION; CUTANEOUS MELANOMA; CLINICAL-RELEVANCE; RADIATION-THERAPY;

D O I：

10.4081/oncol.2019.433

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Sentinel lymph node (SLN) biopsy has become the standard of care for lymph node staging in melanoma and the most important predictor of survival in clinically node-negative disease. Previous guidelines recommend completion lymph node dissection (CLND) in cases of positive SLN; however, the lymph nodes recovered during CLND are only positive in a minority of these cases. Recent evidence suggests that conservative management (i.e. observation) has similar outcomes compared to CLND. We sought to review the most current literature regarding the management of SLN in metastatic melanoma and to discuss potential future directions.

引用

页码：175 / 182

页数：8

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