Carnosic acid, a component of rosemary (Rosmarinus officinalis L.), promotes synthesis of nerve growth factor in T98G human glioblastoma cells

被引：60

作者：

Kosaka, K

Yokoi, T

机构：

[1] Nagase & Co Ltd, Beauty Care Prod Div, Hlth Care Business Grp, Chuo Ku, Tokyo 1038355, Japan

[2] Kobe Gakuin Univ, Fac Pharmaceut Sci, Nishi Ku, Kobe, Hyogo 6512180, Japan

[3] Kobe Gakuin Univ, High Technol Res Ctr, Nishi Ku, Kobe, Hyogo 6512180, Japan

来源：

BIOLOGICAL & PHARMACEUTICAL BULLETIN | 2003年 / 26卷 / 11期

关键词：

nerve growth factor; carnosic acid; carnosol; Rosemary;

D O I：

10.1248/bpb.26.1620

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Nerve growth factor (NGF) is a factor vital for the growth and functional maintenance of nerve tissue. The authors found that a rosemary (Rosmarinus officinalis L.) extract enhanced the production of NGF in T98G human glioblastoma cells. Furthermore, the results indicated that carnosic acid and carnosol, which are major components of the rosemary extract, were able to promote markedly enhanced synthesis of NGF.

引用

收藏

页码：1620 / 1622

页数：3

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