Self-Assembled DNA Hydrogels with Designable Thermal and Enzymatic Responsiveness

被引：372
|
作者：
Xing, Yongzheng [1 ,2 ]
Cheng, Enjun [2 ]
Yang, Yang [2 ]
Chen, Ping [3 ]
Zhang, Tao [3 ]
Sun, Yawei [2 ]
Yang, Zhongqiang [1 ]
Liu, Dongsheng [1 ]
机构：
[1] Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Organ Optoelect & Mol Engn, Beijing 100084, Peoples R China
[2] Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China
[3] Renmin Univ China, Dept Chem, Beijing 100872, Peoples R China
来源：
ADVANCED MATERIALS | 2011年 / 23卷 / 09期
关键词：
PROTEIN; NANOPARTICLES; APTAMER; RELEASE;
D O I：
10.1002/adma.201003343
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An easy and versatile approach to construct DNA hydrogels is reported. The DNA building blocks, a Y-scaffold and a linker, can self-assemble into DNA hydrogels by the hybridization of their "sticky ends". It is shown that the DNA hydrogels undergo a sol-gel transition upon heat or enzymatic treatment, and the responsiveness can be adjusted by tailoring the sequence of the building blocks.
引用
收藏
页码：1117 / 1121
页数：5
相关论文
共 50 条
  • [21] Novel electro self-assembled DNA nanospheres as a drug delivery system for atenolol
    Elkayal, Rehab
    Motawea, Amira
    Reicha, Fikry M.
    Elmezayyen, Ayman S.
    NANOTECHNOLOGY, 2021, 32 (25)
  • [22] Thermal Transport in Self-Assembled Conductive Networks for Thermal Interface Materials
    Hu, Lin
    Evans, William
    Keblinski, Pawel
    JOURNAL OF ELECTRONIC PACKAGING, 2011, 133 (02)
  • [23] Electro-Thermochromic Devices Composed of Self-Assembled Transparent Electrodes and Hydrogels
    Zhou, Yang
    Layani, Michael
    Boey, Freddy Yin Chiang
    Sokolov, Ilan
    Magdassi, Shlomo
    Long, Yi
    ADVANCED MATERIALS TECHNOLOGIES, 2016, 1 (05):
  • [24] Self-Assembled Injectable Peptide Hydrogels Capable of Triggering Antitumor Immune Response
    Xing, Ruirui
    Li, Shukun
    Zhang, Ning
    Shen, Guizhi
    Mohwald, Helmuth
    Yan, Xuehai
    BIOMACROMOLECULES, 2017, 18 (11) : 3514 - 3523
  • [25] Self-assembled natural biomacromolecular fluorescent hydrogels with tunable red edge effects
    Su, Weiwei
    Yin, Juanjuan
    Wang, Ran
    Shi, Mengqian
    Liu, Ping
    Qin, Zhihui
    Xing, Ruirui
    Jiao, Tifeng
    COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2021, 612
  • [26] Dynamic Expression of DNA Complexation with Self-assembled Biomolecular Clusters
    Bartolami, Eline
    Bessin, Yannick
    Gervais, Virginie
    Dumy, Pascal
    Ulrich, Sebastien
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 54 (35) : 10183 - 10187
  • [27] Self-assembled, Programmable DNA Nanodevices for Biological and Biomedical Applications
    Bhatia, Dhiraj
    Wunder, Christian
    Johannes, Ludger
    CHEMBIOCHEM, 2021, 22 (05) : 763 - 778
  • [28] Self-assembled DNA nanomaterials with highly programmed structures and functions
    Li, Zhihao
    Wang, Jie
    Li, Yingxue
    Liu, Xinwen
    Yuan, Quan
    MATERIALS CHEMISTRY FRONTIERS, 2018, 2 (03) : 423 - 436
  • [29] Self-Assembled Phage-Based Colloids for High Localized Enzymatic Activity
    Alarcon-Correa, Mariana
    Guenther, Jan-Philipp
    Troll, Jonas
    Kadiri, Vincent Mauricio
    Bill, Joachim
    Fischer, Peer
    Rothenstein, Dirk
    ACS NANO, 2019, 13 (05) : 5810 - 5815
  • [30] Simple Self-Assembled Targeting DNA Nano Sea Urchin as a Multivalent Drug Carrier
    Zhang, Jingjing
    Wang, Zhenmeng
    Gao, Yansha
    Wu, Zai-Sheng
    ACS APPLIED BIO MATERIALS, 2020, 3 (07): : 4514 - 4521
12345