Cascade C-H Functionalization/Amidation Reaction for Synthesis of Azepinone Derivatives

被引：65

作者：

Bai, Peng ^{[1
]}

Huang, Xing-Fen ^{[1
]}

Xu, Guo-Dong ^{[1
]}

Huang, Zhi-Zhen ^{[1
,2
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310028, Zhejiang, Peoples R China

[2] Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China

来源：

ORGANIC LETTERS | 2016年 / 18卷 / 13期

基金：

中国国家自然科学基金;

关键词：

DIAZO-COMPOUNDS; FREE-AMINE; RH(III)-CATALYZED SYNTHESIS; ALIPHATIC-AMINES; ORTHO-ARYLATION; N BOND; ACTIVATION; ALKENYLATION; AZOBENZENES; C(SP(2))-H;

D O I：

10.1021/acs.orglett.6b01140

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A cascade C-H functionalization/amidation reaction of aminobiaryls with diazomalonates has been developed under rhodium catalysis, affording new azepinone derivatives in moderate to excellent yields.

引用

页码：3058 / 3061

页数：4

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