Updated Results from the Venetoclax (Ven) in Combination with Idasanutlin (Idasa) Arm of a Phase 1b Trial in Elderly Patients (Pts) with Relapsed or Refractory (R/R) AML Ineligible for Cytotoxic Chemotherapy

被引：28

作者：

Daver, Naval G. ^{[1
]}

Garcia, Jacqueline S. ^{[2
]}

Jonas, Brian A. ^{[3
]}

Kelly, Kevin R. ^{[4
]}

Assouline, Sarit ^{[5
]}

Brandwein, Joseph M. ^{[6
]}

Fenaux, Pierre ^{[7
]}

Olin, Rebecca L. ^{[8
]}

Martinelli, Giovanni ^{[9
]}

Paolini, Stefania ^{[10
]}

Pigneux, Arnaud ^{[11
]}

Pollyea, Daniel A. ^{[12
]}

Powell, Bayard L. ^{[13
]}

Roboz, Gail J. ^{[14
]}

Tafuri, Agostino ^{[15
]}

Vey, Norbert ^{[16
]}

Visani, Giuseppe ^{[17
]}

Yee, Karen W. L. ^{[18
]}

Dail, Monique ^{[19
]}

Green, Cherie ^{[20
]}

Kirschbrown, Whitney P. ^{[20
]}

Hong, Wan-Jen ^{[20
]}

Ott, Marion G. ^{[21
]}

Onishi, Maika ^{[20
]}

Wang, Jue ^{[20
]}

Konopleva, Marina Y. ^{[1
]}

Andreeff, Michael ^{[22
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

[2] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA

[3] Univ Calif Davis, Div Hematol & Oncol, Ctr Oncol Hematol Outcomes Res & Training, Sacramento, CA USA

[4] Univ Southern Calif, Los Angeles, CA 90007 USA

[5] McGill Univ, Jewish Gen Hosp, Div Hematol, Montreal, PQ, Canada

[6] Univ Alberta, Div Hematol, Edmonton, AB, Canada

[7] Univ Paris Diderot, Hop St Louis, Paris, France

[8] Univ Calif San Francisco, Div Hematol & Blood & Marrow Transplantat, San Francisco, CA 94143 USA

[9] Ist Sci Romagnolo Studio & Cura Tumori IRST, IRCCS, Meldola, FC, Italy

[10] Univ Bologna, Inst Hematol L & A Seragnoli, Dept Expt Diagnost & Specialty Med, Bologna, Italy

[11] Bordeaux Haut Leveque Univ Hosp, Pessac, France

[12] Univ Colorado, Aurora, CO USA

[13] Wake Forest Baptist Comprehens Canc Ctr, Winston Salem, NC USA

[14] Weill Cornell Med & New York Presbyterian Hosp, New York, NY USA

[15] Univ Hosp St Andrea Sapienza, Hematol, DMCM, Rome, Italy

[16] Inst Paoli Calmettes, Hematol Clin, Marseille, France

[17] Osped San Salvatore, Hematol, Pesaro, Italy

[18] Princess Margaret Canc Ctr, Toronto, ON, Canada

[19] Genentech Inc, Oncol Biomarker Dev, San Francisco, CA USA

[20] Genentech Inc, San Francisco, CA 94080 USA

[21] F Hoffmann La Roche, Basel, Switzerland

[22] Univ Texas MD Anderson Canc Ctr, Sect Mol Hematol & Therapy, Dept Leukemia, Houston, TX USA

来源：

BLOOD | 2019年 / 134卷

关键词：

D O I：

10.1182/blood-2019-123711

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

229

引用

页数：7