Molecular Diagnosis of Bacterial Vaginosis: an Update

被引：128

作者：

Coleman, Jenell S. ^{[1
]}

Gaydos, Charlotte A. ^{[2
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Dept Gynecol & Obstet, Baltimore, MD 21218 USA

[2] Johns Hopkins Univ, Sch Med, Dept Med, Div Infect Dis, Baltimore, MD 21205 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2018年 / 56卷 / 09期

关键词：

bacterial vaginosis; real-time PCR; vaginal flora; GARDNERELLA-VAGINALIS; GRAM-STAIN; PRETERM BIRTH; PCR ASSAY; CRITERIA; IDENTIFICATION; VALIDATION; BIOFILM; WOMEN; RISK;

D O I：

10.1128/JCM.00342-18

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Bacterial vaginosis (BV) is the most common cause of vaginal discharge in reproductive-age women. BV has been associated with poor reproductive outcomes such as preterm delivery, the acquisition of sexually transmitted infections, including HIV, and pelvic inflammatory disease. BV represents the acquisition of a diverse community of anaerobic and facultative bacteria and a reduction in lactobacilli. It can be diagnosed using several tests ranging from clinical indicators, point-of-care tests, and molecular assays. Molecular technologies are objective, are able to detect fastidious bacteria, enable quantitation, and are ideal for self-collected vaginal swabs. This paper reviews the currently available BV diagnostic tests in the United States.

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页数：9

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