Frequency of medically attended events following rapid revaccination with trivalent inactivated influenza vaccine

被引:1
作者
Schmidt, Mark A. [1 ]
Crane, Brad [1 ]
Mullooly, John P. [1 ]
Naleway, Allison L. [1 ]
机构
[1] Kaiser Permanente NW, Ctr Hlth Res, Portland, OR 97227 USA
关键词
Trivalent influenza vaccine; Medically attended events; Influenza; CHILDREN; 6; MONTHS; UNITED-STATES; H5N1; VACCINE; IMMUNOGENICITY; SAFETY; IMMUNIZATION; SERVICES; GENDER; VIRUS;
D O I
10.1016/j.vaccine.2010.09.043
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In 2008, potential temperature compromise of one lot of trivalent inactivated influenza vaccine (TIV) led to the revaccination of 13,210 Kaiser Permanente Northwest members within 28 days of receipt of their initial TIV dose. We conducted a retrospective cohort study to determine if these individuals experienced a higher rate of medically attended events (MAE) than those receiving only one TIV dose. We found no increase in MAE among those rapidly revaccinated (odds ratio 1.08; 95% confidence interval 0.80, 1.45), which may reassure individuals of the safety of revaccination with TIV should it be necessary, thereby leading to increased compliance with influenza vaccination recommendations. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:7713 / 7715
页数:3
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