Sch 65676: A novel fungal metabolite with the inhibitory activity against the cytomegalovirus protease

被引：14
作者：
Chu, M
Mierzwa, R
Truumees, I
King, A
Patel, M
Pichardo, J
Hart, A
Dasmahapatra, B
Das, PR
Puar, MS
机构：
[1] Schering-Plough Research Institute, Kenilworth, NJ 07003
来源：
TETRAHEDRON LETTERS | 1996年 / 37卷 / 23期
关键词：
D O I：
10.1016/0040-4039(96)00748-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new secondary metabolite, Sch 65676 (1), was isolated from the fermentation broth of a fungal culture. The structure of 1 was elucidated based on comprehensive NMR studies including COSY, NOE and HMBC experiments. Compound 1 displays inhibitory activity against the cytomegalovirus (CMV) protease. (C) 1996 Elsevier Science Ltd
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页码：3943 / 3946
页数：4
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