Complete Genome Sequence of Klebsiella pneumoniae Strain TK421, a Conjugative Hypervirulent Isolate

被引：5

作者：

Kochan, Travis J. ^{[1
]}

Ozer, Egon A. ^{[2
]}

Pincus, Nathan B. ^{[1
]}

Fitzpatrick, Margaret A. ^{[3
]}

Hauser, Alan R. ^{[1
,2
]}

机构：

[1] Northwestern Univ, Feinberg Sch Med, Dept Microbiol Immunol, Chicago, IL 60611 USA

[2] Northwestern Univ, Feinberg Sch Med, Dept Med, Div Infect Dis, Chicago, IL 60611 USA

[3] Loyola Univ Chicago, Stritch Sch Med, Dept Med, Div Infect Dis, Maywood, IL USA

来源：

MICROBIOLOGY RESOURCE ANNOUNCEMENTS | 2020年 / 9卷 / 03期

关键词：

LIVER-ABSCESS; VIRULENCE; CEFOTAXIME; ANNOTATION; RESISTANCE;

D O I：

10.1128/MRA.01408-19

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Klebsiella pneumoniae is a Gram-negative bacterium that is a major cause of nosocomial infections worldwide. Here, we present the complete genome sequence of TK421, a clinical bacteremia isolate containing a hypervirulence plasmid carrying tra-associated conjugation machinery genes. Emergence of conjugative hypervirulence plasmids could portend rapid dissemination of hypervirulence among multidrug-resistant K. pneumoniae strains.

引用

页数：3

共 29 条

[1] Genomic Definition of Hypervirulent and Multidrug-Resistant Klebsiella pneumoniae Clonal Groups [J].

Bialek-Davenet, Suzanne ;

Criscuolo, Alexis ;

Ailloud, Florent ;

Passet, Virginie ;

Jones, Louis ;

Delannoy-Vieillard, Anne-Sophie ;

Garin, Benoit ;

Le Hello, Simon ;

Arlet, Guillaume ;

Nicolas-Chanoine, Marie-Helene ;

Decre, Dominique ;

Brisse, Sylvain .

EMERGING INFECTIOUS DISEASES, 2014, 20 (11) :1812-1820

[2] Sequencing and analysis of the large virulence plasmid pLVPK of Klebsiella pneumoniae CG43 [J].

Chen, YT ;

Chang, HY ;

Lai, YC ;

Pan, CC ;

Tsai, SF ;

Peng, HL .

GENE, 2004, 337 :189-198

[3] Type IV secretion:: the Agrobacterium VirB/D4 and related conjugation systems [J].

Christie, PJ .

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2004, 1694 (1-3) :219-234

[4] PROSPECTIVE SURVEY OF COLONIZATION AND INFECTION CAUSED BY EXPANDED-SPECTRUM-BETA-LACTAMASE-PRODUCING MEMBERS OF THE FAMILY ENTEROBACTERIACEAE IN AN INTENSIVE-CARE UNIT [J].

DECHAMPS, C ;

SAUVANT, MP ;

CHANAL, C ;

SIROT, D ;

GAZUY, N ;

MALHURET, R ;

BAGUET, JC ;

SIROT, J .

JOURNAL OF CLINICAL MICROBIOLOGY, 1989, 27 (12) :2887-2890

[5] Carriage of blaKPC-2 by a virulence plasmid in hypervirulent Klebsiella pneumoniae [J].

Dong, Ning ;

Lin, Dachuan ;

Zhang, Rong ;

Chan, Edward Wai-Chi ;

Chen, Sheng .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2018, 73 (12) :3317-3321

[6] Liver abscess caused by magA plus Klebsiella pneumoniae in North America [J].

Fang, FC ;

Sandler, N ;

Libby, SJ .

JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (02) :991-992

[7]

Feng Y, 2018, ANTIMICROB AGENTS CH, V62, DOI [10.1128/AAC.02644-17, 10.1128/aac.02644-17]

[8]

Gu DX, 2018, LANCET INFECT DIS, V18, P37, DOI [10.1016/S1473-3099(17)30489-9, 10.1016/s1473-3099(17)30489-9]

[9] RefSeq: an update on prokaryotic genome annotation and curation [J].

Haft, Daniel H. ;

DiCuccio, Michael ;

Badretdin, Azat ;

Brover, Vyacheslav ;

Chetvernin, Vyacheslav ;

O'Neill, Kathleen ;

Li, Wenjun ;

Chitsaz, Farideh ;

Derbyshire, Myra K. ;

Gonzales, Noreen R. ;

Gwadz, Marc ;

Lu, Fu ;

Marchler, Gabriele H. ;

Song, James S. ;

Thanki, Narmada ;

Yamashita, Roxanne A. ;

Zheng, Chanjuan ;

Thibaud-Nissen, Francoise ;

Geer, Lewis Y. ;

Marchler-Bauer, Aron ;

Pruitt, Kim D. .

NUCLEIC ACIDS RESEARCH, 2018, 46 (D1) :D851-D860

[10] Serum-induced iron-acquisition systems and TonB contribute to virulence in Klebsiella pneumoniae causing primary pyogenic liver abscess [J].

Hsieh, Pei-Fang ;

Lin, Tzu-Lung ;

Lee, Cha-Ze ;

Tsai, Shih-Feng ;

Wang, Jin-Town .

JOURNAL OF INFECTIOUS DISEASES, 2008, 197 (12) :1717-1727

← 1 2 3 →