The advantages of carbon nanoparticles in level VII lymph node dissection in patients with papillary thyroid cancer

被引:9
作者
Chen, Yijun [1 ]
Zhang, Guolie [1 ]
Lin, Yuanmei [1 ]
Zhang, Guoliang [1 ]
Gao, Jian [1 ]
机构
[1] Putian Univ, Dept Thyroid Surg 1, Affiliated Hosp, Putian 351100, Peoples R China
关键词
Carbon nanoparticles (CNs); level VII; papillary thyroid cancer (PTC); central lymph node dissection (CLND); hypoparathyroidism; CENTRAL NECK DISSECTION; TATTOO LOCALIZATION; CENTRAL COMPARTMENT; CARCINOMA; METASTASIS; PREDICTION; MANAGEMENT; THERAPY; CALCIUM;
D O I
10.21037/gs-21-281
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: The characteristics of level VII lymph nodes were explored and the advantages of using carbon nanoparticles (CNs) in papillary thyroid cancer (PTC) surgeries were examined. This was a retrospective study investigating the clinical data of patients with PTC who underwent surgical treatment. Methods: From September 2019 to December 2020, a total of 191 consecutive patients with PTC were retrospectively analyzed. The patients were randomly divided into the CNs group and the control group. CNs were used in the CNs group during the operation. There were 103 cases in the CNs group, including 25 males and 78 females, and 88 cases in the control group, including 21 males and 67 females. Parameters, including the characteristics of dissected lymph nodes in level VII, metastatic rate, postoperative complications, and other inpatient-related indicators, were compared between the two groups. Results: The number of lymph nodes dissected in level VII in the CNs group was significantly greater than that in the control group, and the metastatic rate of black-stained lymph nodes was significantly higher than that of non-black-stained lymph nodes (P<0.05). The postoperative hypoparathyroidism rate in the CNs group was significantly lower than that in the control group (P<0.05). There were no differences in the operation duration, intraoperative blood loss, postoperative drainage duration, or hospitalization days between the two groups (P>0.05). Conclusions: The application of CNs for patients with PTC significantly increased the number of lymph nodes dissected in level VII and helped to protect the parathyroid glands (PGs). Moreover, the use of CNs did not increase the rate of postoperative complications. Thus, CNs may be a simple and safe approach when performing surgery in PTC patients.
引用
收藏
页码:2028 / 2036
页数:9
相关论文
共 27 条
[1]   Prediction of central lymph node metastasis in patients with thyroid papillary microcarcinoma [J].
Akin, Safak ;
Aksoy, Duygu Yazgan ;
Akin, Serkan ;
Kilic, Mehmet ;
Yetisir, Fahri ;
Bayraktar, Miyase .
TURKISH JOURNAL OF MEDICAL SCIENCES, 2017, 47 (06) :1723-1727
[2]   Is routine supplementation therapy (calcium and vitamin D) useful after total thyroidectomy? [J].
Bellantone, R ;
Lombardi, CP ;
Raffaelli, M ;
Boscherini, M ;
Alesina, PF ;
De Crea, C ;
Traini, E ;
Princi, P .
SURGERY, 2002, 132 (06) :1109-1112
[3]   Accuracy of PTH assay and corrected calcium in early prediction of hypoparathyroidism after thyroid surgery [J].
Cavicchi, Ottavio ;
Piccin, Ottavio ;
Caliceti, Umberto ;
Fernandez, Ignacio Javier ;
Bordonaro, Carla ;
Saggese, Domenico ;
Ceroni, Alberto Rinaldi .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2008, 138 (05) :594-600
[4]   Preoperative Localization of Neck Recurrences from Thyroid Cancer: Charcoal Tattooing Under Ultrasound Guidance [J].
Chami, Linda ;
Hartl, Dana ;
Leboulleux, Sophie ;
Baudin, Eric ;
Lumbroso, Jean ;
Schlumberger, Martin ;
Travagli, Jean Paul .
THYROID, 2015, 25 (03) :341-346
[5]   Central lymph node metastasis in papillary thyroid microcarcinoma can be stratified according to the number, the size of metastatic foci, and the presence of desmoplasia [J].
Cho, Soo Youn ;
Lee, Tae Hyun ;
Ku, Yun Hyi ;
IlKim, Hong ;
Lee, Guk Haeng ;
Kim, Min Joo .
SURGERY, 2015, 157 (01) :111-118
[6]   Papillary Thyroid Cancer: Controversies in the Management of Neck Metastasis [J].
Davidson, H. Carter ;
Park, Brian J. ;
Johnson, Jonas T. .
LARYNGOSCOPE, 2008, 118 (12) :2161-2165
[7]  
Gao B, 2015, INT J CLIN EXP MED, V8, P22254
[8]   Charcoal Suspension Tattoo Localization for Differentiated Thyroid Cancer Recurrence [J].
Hartl, Dana M. ;
Chami, Linda ;
Al Ghuzlan, Abir ;
Leboulleux, Sophie ;
Baudin, Eric ;
Schlumberger, Martin ;
Travagli, Jean-Paul .
ANNALS OF SURGICAL ONCOLOGY, 2009, 16 (09) :2602-2608
[9]   2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer [J].
Haugen, Bryan R. ;
Alexander, Erik K. ;
Bible, Keith C. ;
Doherty, Gerard M. ;
Mandel, Susan J. ;
Nikiforov, Yuri E. ;
Pacini, Furio ;
Randolph, Gregory W. ;
Sawka, Anna M. ;
Schlumberger, Martin ;
Schuff, Kathryn G. ;
Sherman, Steven I. ;
Sosa, Julie Ann ;
Steward, David L. ;
Tuttle, R. Michael ;
Wartofsky, Leonard .
THYROID, 2016, 26 (01) :1-133
[10]   Central Neck Dissection for Papillary Thyroid Cancer [J].
Hughes, David T. ;
Doherty, Gerard M. .
CANCER CONTROL, 2011, 18 (02) :83-88