Pain Medication and Global Cognitive Functioning in Dementia Patients with Painful Conditions

被引:13
|
作者
Plooij, Bart [1 ]
van der Spek, Klaas [1 ]
Scherder, Erik J. A. [1 ]
机构
[1] Vrije Univ Amsterdam, Dept Clin Neuropsychol, NL-1081 BT Amsterdam, Netherlands
关键词
NURSING-HOME RESIDENTS; ANALGESIC MEDICATION; SELF-ASSESSMENT; MANAGEMENT; SCALE; VALIDATION; PEOPLE;
D O I
10.2165/11630850-000000000-00000
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Background: Dementia patients are at an increased risk for undertreatment of pain, compared with older people without dementia, suggesting a relationship between pain medication prescription and cognitive functioning. Studies on a possible relationship between pain medication and cognitive functioning in dementia patients are ambiguous. Objective: The objective of the study was to investigate whether a relationship between cognition and pain medication is present in patients with dementia with painful conditions. Methods: Initially, 187 people living in Dutch nursing homes participated in the study. Sixty-one patients with dementia and at least one painful condition were included in the final analysis. Logistic regression analyses were conducted to examine the relationship between global cognitive functioning (Mini-Mental State Examination score) and pain medication for the total group and for the largest dementia subgroup, i.e. patients with Alzheimer's disease. Results: No relationships were found between global cognitive functioning and pain medication in the total group and in the group of patients with Alzheimer's disease. Forty-five percent of the participants did not receive any pain medication, despite the presence of a painful condition. Conclusion: Undertreatment of pain in dementia seems to be independent of global cognitive functioning. The use of observational scales, to increase the awareness of other signs of pain, e.g. physical inactivity and behavioural disturbances, is recommended. Even if there is no obvious cause for behavioural disturbances, treatment with relatively mild pain medication should be considered.
引用
收藏
页码:377 / 384
页数:8
相关论文
共 50 条
  • [1] Pain Medication and Global Cognitive Functioning in Dementia Patients with Painful Conditions
    Bart Plooij
    Klaas van der Spek
    Erik J. A. Scherder
    Drugs & Aging, 2012, 29 : 377 - 384
  • [2] CHRONIC PAIN'S PAINFUL IMPACT ON COGNITIVE FUNCTIONING
    Azer, Lilian
    Skoblow, Hanamori
    Flores, Eileen
    Llaneza, Danielle
    Zhang, Weiwei
    D'Antonio, Patricia
    INNOVATION IN AGING, 2022, 6 : 380 - 380
  • [3] DISTURBANCES OF SLEEP AND COGNITIVE-FUNCTIONING IN PATIENTS WITH DEMENTIA
    LOEWENSTEIN, RJ
    WEINGARTNER, H
    GILLIN, JC
    KAYE, W
    EBERT, M
    MENDELSON, WB
    NEUROBIOLOGY OF AGING, 1982, 3 (04) : 371 - 377
  • [4] The impact of pain on the course of ADL functioning in patients with dementia
    Van Dalen-Kok, Annelore H.
    Pieper, Marjoleine J. C.
    de Waal, Margot W. M.
    van Der Steen, Jenny T.
    Scherder, Erik J. A.
    Achterberg, Wilco P.
    AGE AND AGEING, 2021, 50 (03) : 906 - 913
  • [5] Emotional and cognitive functioning in patients with chronic pain
    Lutricuso, Sara
    Laera, Domenico
    Losole, Jole
    Puntillo, Filomena
    Taurino, Alessandro
    De Caro, Maria Fara
    PSYCHOTHERAPY AND PSYCHOSOMATICS, 2019, 88 : 78 - 78
  • [6] Perception of breakthrough pain in patients with chronic painful conditions
    Pizzi, L. T.
    Lee, S. P.
    Richardson, D.
    Cobb, N.
    Leas, B.
    Toner, R.
    Pracilio, V
    Ballas, S.
    Ashkenazi, A.
    Derk, C. T.
    Wang, D.
    DeSoussa, E.
    VALUE IN HEALTH, 2007, 10 (06) : A466 - A466
  • [7] Cholinergic circuitry functioning in patients with vascular cognitive impairment - no dementia
    Bella, Rita
    Cantone, Mariagiovanna
    Lanza, Giuseppe
    Ferri, Raffaele
    Vinciguerra, Luisa
    Puglisi, Valentina
    Pennisi, Manuela
    Ricceri, Riccardo
    Di Lazzaro, Vincenzo
    Pennisi, Giovanni
    BRAIN STIMULATION, 2016, 9 (02) : 225 - 233
  • [8] Loss in Executive Functioning Best Explains Changes in Pain Responsiveness in Patients with Dementia-Related Cognitive Decline
    Kunz, Miriam
    Mylius, Veit
    Schepelmann, Karsten
    Lautenbacher, Stefan
    BEHAVIOURAL NEUROLOGY, 2015, 2015
  • [9] Predictors of global cognitive functioning in drug addicted patients
    Santos, O.
    Penalver, J. C.
    Bourin, M.
    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2006, 9 : S172 - S173
  • [10] Cognitive Functioning of Geriatric Patients: Is Hypovitaminosis D the Next Marker of Cognitive Dysfunction and Dementia?
    Lukaszyk, Ewelina
    Bien-Barkowska, Katarzyna
    Bien, Barbara
    NUTRIENTS, 2018, 10 (08):