Morbidity and Mortality of Meningioma Resection Increases in Octogenarians

被引:38
作者
Steinberger, Jeremy [1 ]
Bronheim, Rachel S. [2 ]
Vempati, Prashant [2 ]
Oermann, Eric K. [1 ]
Ladner, Travis R. [1 ]
Lee, Nathan J. [2 ]
Kothari, Parth [2 ]
Caridi, John M. [1 ]
Shrivastava, Raj K. [1 ]
机构
[1] Icahn Sch Med Mt Sinai, Dept Neurosurg, New York, NY 10029 USA
[2] Icahn Sch Med Mt Sinai, Dept Med Educ, New York, NY 10029 USA
关键词
Craniotomy; Meningioma; Octogenarian; Postoperative complications; NATIONWIDE INPATIENT SAMPLE; INTRACRANIAL MENINGIOMAS; VENOUS THROMBOEMBOLISM; 9TH DECADE; SURGERY; RISK; CRANIOTOMY; COMPLICATIONS; RADIOTHERAPY; THROMBOSIS;
D O I
10.1016/j.wneu.2017.09.021
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
BACKGROUND: The incidence of meningioma has increased drastically recently, particularly in older adults. Surgical intervention has the potential to reduce neurologic symptoms and achieve favorable, long-term outcomes. There is considerable variability in the literature examining the relationship between age and outcomes after meningioma surgery. The objective of this study was to identify the relationship between age and postoperative complications after craniotomy for resection of meningioma. METHODS: The American College of Surgeons National Surgical Quality Improvement Program database was used to identify patients undergoing craniotomy for meningioma resection between 2005 and 2012. Multivariate analysis was used to identify associations between age and postoperative complications. RESULTS: Age > 80 years is an independent risk factor for any complication (odds ratio [OR], 2.374; 95% confidence interval [CI], 1.3-4.4; P [0.015), death within 30 days of surgery (OR, 15.7; 95% CI, 3.0-81.0; P < 0.001), and length of stay > 5 days (OR, 3.2; 95% CI, 1.8-5.6; P < 0.001). CONCLUSIONS: Advanced age, particularly > 80 years, is an independent predictor of morbidity and mortality in patients undergoing craniotomy for resection of meningioma. As such, it should be considered in preoperative optimization and risk stratification.
引用
收藏
页码:E16 / E23
页数:8
相关论文
共 39 条
[1]   Analysis of Venous Thromboembolism Risk in Patients Undergoing Craniotomy [J].
Algattas, Hanna ;
Kimmell, Kristopher T. ;
Vates, G. Edward ;
Jahromi, Babak S. .
WORLD NEUROSURGERY, 2015, 84 (05) :1372-1379
[2]   Trends in intracranial meningioma surgery and outcome: a Nationwide Inpatient Sample database analysis from 2001 to 2010 [J].
Ambekar, Sudheer ;
Sharma, Mayur ;
Madhugiri, Venkatesh S. ;
Nanda, Anil .
JOURNAL OF NEURO-ONCOLOGY, 2013, 114 (03) :299-307
[3]  
American College of Surgeon National Surgical Quality Improvement Program, 2013, ACS NSQIP US GUID 20
[4]   Patterns of Care and Outcomes of Adjuvant Radiotherapy for Meningiomas: A Surveillance, Epidemiology, and End Results and Medicare Linked Analysis [J].
Amsbaugh, Mark ;
Ugiliweneza, Beatrice ;
Burton, Eric ;
Skirboll, Stephen ;
Woo, Shiao ;
Boakye, Max .
CUREUS, 2016, 8 (04)
[5]   TREATMENT OF INTRACRANIAL MENINGIOMAS IN PATIENTS OVER 70 YEARS OLD [J].
ARIENTA, C ;
CAROLI, M ;
CROTTI, F ;
VILLANI, R .
ACTA NEUROCHIRURGICA, 1990, 107 (1-2) :47-55
[6]   INTRACRANIAL MENINGIOMAS IN THE AGED - SURGICAL OUTCOME IN THE ERA OF COMPUTED-TOMOGRAPHY [J].
AWAD, IA ;
KALFAS, I ;
HAHN, JF ;
LITTLE, JR .
NEUROSURGERY, 1989, 24 (04) :557-560
[7]   Meningioma resection in the elderly: Nationwide inpatient sample, 1998-2002 [J].
Bateman, BT ;
Pile-Spellman, J ;
Gutin, PH ;
Berman, MF .
NEUROSURGERY, 2005, 57 (05) :866-871
[8]   Meningioma surgery in the elderly: A case-control study assessing morbidity and mortality [J].
Black, P ;
Kathiresan, S ;
Chung, W .
ACTA NEUROCHIRURGICA, 1998, 140 (10) :1013-+
[9]   Impact of age on complications and outcome in meningioma surgery [J].
Boviatsis, Efstathios J. ;
Bouras, Triantafyllos I. ;
Kouyialis, Andreas T. ;
Themistocleous, Marios S. ;
Sakas, Damianos E. .
SURGICAL NEUROLOGY, 2007, 68 (04) :407-411
[10]   Surgery for meningioma in the elderly and long-term survival: comparison with an age- and sex-matched general population and with younger patients [J].
Brokinkel, Benjamin ;
Holling, Markus ;
Spille, Dorothee Caecilia ;
Hess, Katharina ;
Sauerland, Cristina ;
Bleimueller, Caroline ;
Paulus, Werner ;
Woelfer, Johannes ;
Stummer, Walter .
JOURNAL OF NEUROSURGERY, 2017, 126 (04) :1201-1211