An Intramolecular Charge Transfer (ICT)-Based Fluorescent probe Hydrogen Sulphide under pH Control Strategy

Hydrogen sulfide (H2S) and pH playa most important role in vivo and environment. A fluorescent probe for fast and sensitive detection of H2S and pH are of vital importance for research their functions. A naphthalimide-based fluorescent probe L has been designed arid synthesized based on intramolecular charge transfer (ICT) mechanism by utilizing azide as recognition site. The probe L has demonstrated good stability in the pH range of 4 similar to 11. It showed satisfactory sensitivity and rapidly response (less than 3 min) to H2S. An excellent linear relationship (R-2 = 0.99823) displayed in the range of H2S concentrations from 0 mu mol.L-1 to 20 mu.mol.L-1 and the detection limit was 1.18. Furthermore, in the present 30 eqUiV. 1-12S, it was successfully applied to detection of pH with good linear relationship (R-2-0.98764) in the pH range of 2 similar to 6.5. This methods provide a reference for detection of H2S and pH value in the presence of 30 equiv. H2S, which have potential aPPlicati n PmsPects in analYtical detection and pathological analysis.