Solution phase parallel synthesis of 4-aminophenyl ethers using a carboxyl-functionalized ionic liquid as support

被引：16

作者：

Peng, YQ ^{[1
]}

Yi, FP ^{[1
]}

Song, GH ^{[1
]}

Zhang, Y ^{[1
]}

机构：

[1] E China Univ Sci & Technol, Inst Pesticide & Pharmaceut, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

来源：

MONATSHEFTE FUR CHEMIE | 2005年 / 136卷 / 10期

关键词：

parallel synthesis; functional ionic liquid; supports; 4-aminophenyl ethers; combinatorial chemistry;

D O I：

10.1007/s00706-005-0361-4

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A small sortiment of 4-aminophenyl ether derivatives was constructed with good yields and purities via Williamson reaction using the carboxyl-functionalized ionic liquid [cmmim][BF4] as soluble support. The recovered ionic liquid could be reused for several times with similar capacity.

引用

页码：1751 / 1755

页数：5

共 18 条

[1] Synthesis and preliminary use of novel acrylic ester-derived task-specific ionic liquids
Anjaiah, S
Chandrasekhar, S
Grée, R
[J]. TETRAHEDRON LETTERS, 2004, 45 (03) : 569 - 571
[2] THE SN MECHANISM IN AROMATIC COMPOUNDS .9. SOME REACTIONS OF POLYNITRODIARYL ETHERS
BECKWITH, AL
MILLER, J
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1954, 19 (09) : 1416 - 1423
[3] New synthetic method of aromatic ethers under microwave irradiation in dry media.
Bogdal, D
Pielichowski, J
Boron, A
[J]. SYNTHETIC COMMUNICATIONS, 1998, 28 (16) : 3029 - 3039
[4] Development of a novel ionic support and its application in the ionic liquid phase assisted synthesis of a potent antithrombotic
de Kort, M
Tuin, AW
Kuiper, S
Overkleeft, HS
van der Marel, GA
Buijsman, RC
[J]. TETRAHEDRON LETTERS, 2004, 45 (10) : 2171 - 2175
[5] Design, synthesis, and evaluation of small-molecule libraries
Ellman, JA
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1996, 29 (03) : 132 - 143
[6] Efficient combination of task-specific ionic liquid and microwave dielectric heating applied to one-pot three component synthesis of a small library of 4-thiazolidinones
Fraga-Dubreuil, J
Bazureau, JP
[J]. TETRAHEDRON, 2003, 59 (32) : 6121 - 6130
[7] Grafted ionic liquid-phase-supported synthesis of small organic molecules
Fraga-Dubreuil, J
Bazureau, JP
[J]. TETRAHEDRON LETTERS, 2001, 42 (35) : 6097 - 6100
[8] Organic chemistry on solid supports
Fruchtel, JS
Jung, G
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1996, 35 (01): : 17 - 42
[9] Organic synthesis on soluble polymer supports: Liquid-phase methodologies
Gravert, DJ
Janda, KD
[J]. CHEMICAL REVIEWS, 1997, 97 (02) : 489 - 509
[10] The 6-alkyloxyquinaldines
Gutekunst, GO
Gray, HL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1922, 44 : 1741 - 1746

← 1 2 →