Ag-Catalyzed Thiocyanofunctionalization of Terminal Alkynes To Access Alkynylthiocyanates and α-Thiocyanoketones

被引：54
作者：
See, Jie Yang [1 ]
Zhao, Yu [1 ]
机构：
[1] Natl Univ Singapore, Dept Chem, 3 Sci Dr 3, Singapore 117543, Singapore
来源：
ORGANIC LETTERS | 2018年 / 20卷 / 23期
关键词：
ONE-POT SYNTHESIS; S BOND FORMATION; C-H; SULFUR; THIOCYANATION; ACID; CHEMISTRY; HYDRATION; REAGENT; STRAIGHTFORWARD;
D O I：
10.1021/acs.orglett.8b03162
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Unprecedented one-pot thiocyanofunctionalizations of terminal alkynes to deliver alkynylthiocyanates and alpha-thiocyanoketones using a silver-catalyzed procedure or under silver/gold relay catalysis is reported. These synthetically valuable organothiocyanates are accessed in high efficiency, and their derivatization into a variety of valuable sulfur-containing heterocycles and sulfides has also been demonstrated.
引用
收藏
页码：7433 / 7436
页数：4
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