Synthesis of alkylated indolizidine alkaloids via Pummerer mediated cyclization:: synthesis of (±)-indolizidine 167B, (±)-5-butylindolizidine and (±)-monomorine I

被引：20

作者：

Kuhakarn, Chutima ^{[1
]}

Seehasombat, Phachanee ^{[1
]}

Jaipetch, Thaworn ^{[2
]}

Pohmakotr, Manat ^{[1
]}

Reutrakul, Vichai ^{[1
]}

机构：

[1] Mahidol Univ, Fac Sci, Dept Chem, Bangkok 10400, Thailand

[2] Mahidol Univ, Saiyok 71150, Kanchanaburi, Thailand

来源：

TETRAHEDRON | 2008年 / 64卷 / 08期

关键词：

D O I：

10.1016/j.tet.2007.12.013

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The syntheses of indolizidine alkaloids, i.e., (+/-)-coniceine, (+/-)-indolizidine 167B, (+/-)-5-butylindolizidine and (+/-)-monomorine I via Pummerer cyclization are described. The key step is the transformation of lactam sulfoxide to bicyclic lactam via the Pummerer cyclization. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：1663 / 1670

页数：8

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