Lactose intolerance: myths and facts. An update

被引:0
作者
Toca, M. del Carmen [1 ]
Fernandez, Adriana [2 ]
Orsi, Marina [3 ]
Tabacco, Omar [4 ]
Vinderola, Gabriel [5 ]
机构
[1] Consultorios Med Pediat, Ramos Mejia, Argentina
[2] Hosp Ninos Sor Maria Ludovica, Dept Nutr & Diet Therapy, La Plata, Argentina
[3] Hosp Italiano Buenos Aires, Dept Pediat Gastroenterol & Hepatol, Buenos Aires, DF, Argentina
[4] Sanatorio Ninos Rosario, Rosario, Argentina
[5] Univ Nacl Litoral, Univ Nacl Litoral UNL, Consejo Nacl Invest Cient & Tecn, CONICET,Inst Ind Dairy Sci,Natl Sci & Tech Res Co, Santa Fe, Argentina
来源
ARCHIVOS ARGENTINOS DE PEDIATRIA | 2021年
关键词
lactose; human milk; lactase; microbiota; lactose intolerance; ABSORPTION; NUTRITION; PRETERM;
D O I
10.5546/aap.2022.eng.59
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Lactose isthe main carbohydrate presentin human milk. It is a disaccharide made up of glucose and galactose. It is produced in the mammary glands, regardless of maternal diet. In addition to providing energy, it is the only source of dietary galactose, necessary for macromolecule synthesis, including oligosaccharides, glycoproteins, and glycolipids. It favors calcium, magnesium, and zinc absorption and retention. Its digestion by lactase and subsequent absorption occurs in the small intestine. Lactase deficiency may be classified into congenital primary (very rare), late-onset primary or secondary due to an injury of the intestine; it may cause intolerance with pain, abdominal distension, abdominal gas, and diarrhea. In the colon, it may be hydrolyzed by bifidobacteria and lactobacilli. The nutritional management of intolerance should always preserve breastfeeding. Lactose reduction or elimination should be transient, and eliminated food should be replaced with other similar in calorie, protein, mineral, and vitamin content.
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页数:8
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