Fluid shear stress modulation of gene expression in endothelial cells

被引：0

作者：

Braddock, M ^{[1
]}

Schwachtgen, JL ^{[1
]}

Houston, P ^{[1
]}

Dickson, MC ^{[1
]}

Lee, MJ ^{[1
]}

Campbell, CJ ^{[1
]}

机构：

[1] Glaxo Wellcome Med Res Ctr, Vasc Dis Res Unit, Stevenage SG1 2NY, Herts, England

来源：

NEWS IN PHYSIOLOGICAL SCIENCES | 1998年 / 13卷

关键词：

D O I：

暂无

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

The vascular endothelium, lining the blood vessel wall, is constantly exposed to wad shear stresses generated by flowing blood. Gene regulation, critical for endothelial cell function, depends on complex interactions at the promoter level and utilizes overlapping signal transduction cascades to activate the expression of genes involved in many biological processes.

引用

页码：241 / 246

页数：6

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