The Role of IgE Production in the Pathophysiology of Rhinitis and Rhinosinusitis

被引：3

作者：

Hoddeson, Elizabeth K. ^{[1
]}

Wise, Sarah K. ^{[1
]}

机构：

[1] Emory Univ, Dept Otolaryngol, Atlanta, GA 30322 USA

来源：

CURRENT ALLERGY AND ASTHMA REPORTS | 2011年 / 11卷 / 03期

关键词：

Rhinitis; Rhinosinusitis; Allergy; IgE; Immunoglobulin E; Local production; Allergic rhinitis; Superantigen; Acute rhinosinusitis; Allergic fungal sinusitis; Chronic sinusitis; Chronic rhinosinusitis; Allergic fungal rhinosinusitis; Nasal polyposis; SEASONAL ALLERGIC RHINITIS; ANTIGEN-SPECIFIC IGE; CELLS; EXPRESSION; CHALLENGE; SINUSITIS; DIAGNOSIS; MUCOSA;

D O I：

10.1007/s11882-011-0181-z

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

A multitude of potential etiologies exist for rhinitis and rhinosinusitis. These sinonasal disorders are heterogeneous entities that are best understood by evaluating the causative factors in each individual patient. More precise diagnosis permits accurate and effective treatment. The association of allergy with sinonasal symptoms has been described for decades; however, the specific relationship between allergy, rhinitis, and rhinosinusitis is complex. Considering allergy in terms of a systemic atopic disorder, along with a local inflammatory process mediated by IgE production in sinonasal tissues, is helpful in unveiling the complex connection between allergy, rhinitis, and rhinosinusitis. This article reviews recent literature regarding local IgE and sinonasal inflammatory conditions.

引用

页码：230 / 235

页数：6

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