Immunotherapy: a new alternative treatment for head and neck squamous cell carcinoma

被引：1
|
作者：
Bron, Luc [1 ]
Romero, Pedro [2 ]
机构：
[1] CHU Vaudois, Serv ORL Chirurg Cervicofaciale, CH-1011 Lausanne, Switzerland
[2] Inst Ludwig Rech Canc Epalinges, Div Onco Immunol, Lausanne, Switzerland
来源：
BULLETIN DU CANCER | 2007年 / 94卷 / 09期
关键词：
head and neck; squamous cell carcinoma; immunotherapy;
D O I：
10.1684/bdc.2007.0426
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In the past decades, prognosis of head and neck squamous cell carcinoma (HNSCC) has not improved even though treatment has made substantial progress, Since the description of immune response against some cancers, antitumoral immunotherapy has been studied to be used as adjunctive treatment in various cancer types. This article review contributions made in the field of immunotherapy on HNSCC in the past few years, It appears that this approach may play an important role in the treatment of head and neck squamous cell carcinoma. Among various TAAs, cancer testis antigens family may be promising candidates for specific immune therapy in HNSCC. Ongoing studies will confirm whether expression CTAs generate an immune response in clinical vaccine trials.
引用
收藏
页码：793 / 797
页数：5
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