Cutaneous sebaceous carcinoma

被引：14
作者：
Wu, Albert [1 ]
Rajak, Saul N. [2 ]
Huilgol, Shyamala C. [1 ,3 ]
James, Craig [4 ]
Selva, Dinesh [3 ,5 ]
机构：
[1] Univ Adelaide, Royal Adelaide Hosp, Dept Dermatol, Adelaide, SA, Australia
[2] Brighton & Sussex Univ Hosp, Sussex Eye Hosp, Brighton, E Sussex, England
[3] Univ Adelaide, Royal Adelaide Hosp, Adelaide Skin & Eye Ctr, Adelaide, SA, Australia
[4] Univ Adelaide, Royal Adelaide Hosp, Clinpath Labs, Adelaide, SA, Australia
[5] Univ Adelaide, Royal Adelaide Hosp, South Australian Inst Ophthalmol, Adelaide, SA, Australia
来源：
AUSTRALASIAN JOURNAL OF DERMATOLOGY | 2020年
关键词：
basal cell carcinoma; Lynch syndrome; Mohs; skin cancer; squamous cell carcinoma; Muir-Torre syndrome; LYMPH-NODE BIOPSY; COMPUTED TOMOGRAPHY/COMPUTED TOMOGRAPHY; MOHS MICROGRAPHIC SURGERY; AMERICAN JOINT COMMITTEE; TOPICAL MITOMYCIN-C; GLAND CARCINOMA; CELL-CARCINOMA; T CATEGORY; CHEMOTHERAPY; MANAGEMENT;
D O I：
10.1111/ajd.13234
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Cutaneous sebaceous carcinoma occurs almost exclusively on the head and neck and has a significant propensity for recurrence and metastasis. It is easily mistaken for benign conditions, resulting in inappropriate management. Thus, it is important to maintain a high index of suspicion. Despite previous reports, sebaceous carcinoma may occur with similar frequency in Asians and whites. Recent genetic data suggest there are multiple mutational groups of sebaceous carcinoma, paving the way for targeted treatment. After a diagnosis, investigations for staging and for Muir-Torre syndrome should be considered. The available evidence on the treatment options for sebaceous carcinoma is discussed, and specific recommendations for management are made.
引用
收藏
页码：e283 / e292
页数：10
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