The C-3 chlorination of 2-aryl-1-hydroxyindoles

被引：3

作者：

Chirkova, Zhanna V. ^{[1
]}

Kabanova, Mariya V. ^{[1
]}

Filimonov, Sergey I. ^{[1
]}

Abramov, Igor G. ^{[1
]}

Samet, Alexander V. ^{[2
]}

Stashina, Galina A. ^{[2
]}

机构：

[1] Yaroslavl State Tech Univ, Yaroslavl 150023, Russia

[2] Russian Acad Sci, ND Zelinsky Inst Organ Chem, Moscow 119991, Russia

来源：

MENDELEEV COMMUNICATIONS | 2017年 / 27卷 / 05期

关键词：

TERTIARY AMINE OXIDES; EFFICIENT SYNTHESIS; MONOAMINE-OXIDASE; IN-SITU; HALOGENATION; DERIVATIVES; OXIDATION;

D O I：

10.1016/j.mencom.2017.09.023

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chlorination of 2-aryl-1-hydroxyindole-5,6-dicarbonitriles with N-chlorosuccinimide affords previously unknown 3,3-dichloro-3H-indole 1-oxides instead of the expected 1-hydroxy3-chloroindoles. The latter can be prepared in good yields by treatment of the above 3,3-dichloro-3H-indole 1-oxides with piperidine in ethanol.

引用

页码：498 / 499

页数：2

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