BalestraWeb: efficient online evaluation of drug-target interactions

被引：18

作者：

Cobanoglu, Murat Can ^{[1
,2
]}

Oltvai, Zoltan N. ^{[1
,3
]}

Taylor, D. Lansing ^{[1
,2
]}

Bahar, Ivet ^{[1
]}

机构：

[1] Univ Pittsburgh, Sch Med, Dept Computat & Syst Biol, Pittsburgh, PA 15260 USA

[2] Univ Pittsburgh, Drug Discovery Inst, Pittsburgh, PA 15260 USA

[3] Univ Pittsburgh, Sch Med, Dept Pathol, Pittsburgh, PA 15213 USA

来源：

BIOINFORMATICS | 2015年 / 31卷 / 01期

关键词：

PHARMACOLOGY; PARADIGM;

D O I：

10.1093/bioinformatics/btu599

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A Summary: BalestraWeb is an online server that allows users to instantly make predictions about the potential occurrence of interactions between any given drug-target pair, or predict the most likely interaction partners of any drug or target listed in the DrugBank. It also permits users to identify most similar drugs or most similar targets based on their interaction patterns. Outputs help to develop hypotheses about drug repurposing as well as potential side effects.

引用

页码：131 / 133

页数：3

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