Severity of clostridium difficile associated disease (CDAD) in allogeneic stem cell transplant recipients: Evaluation of a CDAD severity grading system

被引：30
作者：
Dubberke, Erik R.
Sadhu, Justin
Gatti, Robert
Reske, Kimberly A.
DiPersio, John F.
Devine, Steven M.
Fraser, Victoria J.
机构：
[1] Washington Univ, Sch Med, Div Infect Dis, St Louis, MO 63110 USA
[2] Washington Univ, Sch Med, Div Oncol, St Louis, MO USA
[3] Univ Missouri, Sch Dent, Kansas City, MO USA
来源：
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY | 2007年 / 28卷 / 02期
关键词：
D O I：
10.1086/511792
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
The purpose of this study was to develop and test a Clostridium difficile - associated disease ( CDAD) grading system based on presenting symptoms in allogeneic stem cell transplant recipients. Patients with severe CDAD had significantly shorter median survival times and more adverse outcomes than patients with mild or moderate CDAD.
引用
收藏
页码：208 / 211
页数：4
相关论文
共 20 条
  • [1] Clostridium difficile infection in patients with neutropenia
    Altclas, J
    Requejo, A
    Jaimovich, G
    Milovic, V
    Feldman, L
    [J]. CLINICAL INFECTIOUS DISEASES, 2002, 34 (05) : 723 - 723
  • [2] Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: An international consensus
    Ascioglu, S
    Rex, JH
    de Pauw, B
    Bennett, JE
    Bille, J
    Crokaert, F
    Denning, DW
    Donnelly, JP
    Edwards, JE
    Erjavec, Z
    Fiere, D
    Lortholary, O
    Maertens, J
    Meis, JF
    Patterson, TF
    Ritter, J
    Selleslag, D
    Shah, PM
    Stevens, DA
    Walsh, TJ
    [J]. CLINICAL INFECTIOUS DISEASES, 2002, 34 (01) : 7 - 14
  • [3] High prevalence of diarrhea but infrequency of documented Clostridium difficile in autologous peripheral blood progenitor cell transplant recipients
    Avery, R
    Pohlman, B
    Adal, K
    Bolwell, B
    Goldman, M
    Kalaycio, M
    Hall, G
    Andresen, S
    Mossad, S
    Schmitt, S
    Mason, P
    Longworth, D
    [J]. BONE MARROW TRANSPLANTATION, 2000, 25 (01) : 67 - 69
  • [4] Incidence and outcome of Clostridium difficile infection following autologous peripheral blood stem cell transplantation
    Bilgrami, S
    Feingold, JM
    Dorsky, D
    Edwards, RL
    Bona, RD
    Khan, AM
    Rodriguez-Pinero, F
    Clive, J
    Tutschka, PJ
    [J]. BONE MARROW TRANSPLANTATION, 1999, 23 (10) : 1039 - 1042
  • [5] Outbreak of Clostridium difficile-related diarrhoea in an adult oncology unit:: risk factors and microbiological characteristics
    Blot, E
    Escande, MC
    Besson, D
    Barbut, F
    Granpeix, C
    Asselain, B
    Falcou, MC
    Pouillart, P
    [J]. JOURNAL OF HOSPITAL INFECTION, 2003, 53 (03) : 187 - 192
  • [6] Clostridium difficile infection in allogeneic stem cell transplant recipients is associated with severe graft-versus-host disease and non-relapse mortality
    Chakrabarti, S
    Lees, A
    Jones, SG
    Milligan, DW
    [J]. BONE MARROW TRANSPLANTATION, 2000, 26 (08) : 871 - 876
  • [7] CLOSTRIDIUM-DIFFICILE CAUSING SEPSIS AND AN ACUTE ABDOMEN IN CRITICALLY ILL PATIENTS
    CHATILA, W
    MANTHOUS, CA
    [J]. CRITICAL CARE MEDICINE, 1995, 23 (06) : 1146 - 1150
  • [8] Clostridium difficile colitis causing toxic megacolon, severe sepsis and multiple organ dysfunction syndrome
    Dobson, G
    Hickey, C
    Trinder, J
    [J]. INTENSIVE CARE MEDICINE, 2003, 29 (06) : 1030 - 1030
  • [9] CDC DEFINITIONS FOR NOSOCOMIAL INFECTIONS, 1988
    GARNER, JS
    JARVIS, WR
    EMORI, TG
    HORAN, TC
    HUGHES, JM
    [J]. AMERICAN JOURNAL OF INFECTION CONTROL, 1988, 16 (03) : 128 - 140
  • [10] Clostridium difficile infection in patients with neutropenia
    Gorschlüter, M
    Glasmacher, A
    Hahn, C
    Schakowski, F
    Ziske, C
    Molitor, E
    Marklein, G
    Sauerbruch, T
    Schmidt-Wolf, IGH
    [J]. CLINICAL INFECTIOUS DISEASES, 2001, 33 (06) : 786 - 791
12