Photodynamic therapy - Aspects of pain management

被引：53
作者：
Fink, Christine [1 ]
Enk, Alexander [1 ]
Gholam, Patrick [1 ]
机构：
[1] Heidelberg Univ, Dept Dermatol, D-69120 Heidelberg, Germany
来源：
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT | 2015年 / 13卷 / 01期
关键词：
NONMELANOMA SKIN-CANCER; COLD-AIR ANALGESIA; PROTOPORPHYRIN-IX FLUORESCENCE; ACTINIC KERATOSES; 5-AMINOLEVULINIC ACID; INTERNATIONAL CONSENSUS; METHYL AMINOLEVULINATE; FLUENCE RATES; LESS PAINFUL; DOUBLE-BLIND;
D O I：
10.1111/ddg.12546
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Topical photodynamic therapy (PDT) is a highly effective and safe treatment method for actinic keratoses with an excellent cosmetic outcome and is commonly used for the therapy of large areas of photodamaged skin with multiple clinically manifest and subclinical lesions. However, the major drawback of photodynamic therapy is the pain experienced during the treatment that can be intense and sometimes even intolerable for patients, requiring interruption or termination of the process. Several strategies for controlling pain during photodynamic therapy have been studied but few effective methods are currently available. Therefore, this review puts the spotlight on predictors on pain intensity and aspects of pain management during photodynamic therapy.
引用
收藏
页码：15 / 22
页数：8
相关论文
共 42 条
[1]   Solar (actinic) keratosis is squamous cell carcinoma [J].
Ackerman, A. B. ;
Mones, J. M. .
BRITISH JOURNAL OF DERMATOLOGY, 2006, 155 (01) :9-22
[2]   The impact of different fluence rates on pain and clinical outcome in patients with actinic keratoses treated with photodynamic therapy [J].
Apalla, Zoi ;
Sotiriou, Eleni ;
Panagiotidou, Despina ;
Lefaki, Ioanna ;
Goussi, Christina ;
Ioannides, Demetris .
PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE, 2011, 27 (04) :181-185
[3]   Pain during topical photodynamic therapy: uncomfortable and unpredictable [J].
Arits, A. H. M. M. ;
van de Weert, M. M. ;
Nelemans, P. J. ;
Kelleners-Smeets, N. W. J. .
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2010, 24 (12) :1452-1457
[4]   In vitro and in vivo comparison of two different light sources for topical photodynamic therapy [J].
Babilas, P ;
Kohl, E ;
Maisch, T ;
Bäcker, H ;
Gross, B ;
Branzan, AL ;
Bäumler, W ;
Landthaler, M ;
Karrer, S ;
Szeimies, RM .
BRITISH JOURNAL OF DERMATOLOGY, 2006, 154 (04) :712-718
[5]   Effect of subcutaneous infiltration anesthesia on pain in photodynamic therapy: A controlled open pilot trial [J].
Borelli, Claudia ;
Herzinger, Thomas ;
Merk, Kathrin ;
Berking, Carola ;
Kunte, Christian ;
Plewig, Gerd ;
Degitz, Klaus .
DERMATOLOGIC SURGERY, 2007, 33 (03) :314-318
[6]   Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: An international consensus [J].
Braathen, Lasse R. ;
Szeimies, Rolf-Markus ;
Basset-Seguin, Nicole ;
Bissonnette, Robert ;
Foley, Peter ;
Pariser, David ;
Roelandts, Rik ;
Wennberg, Ann-Marie ;
Morton, Colin A. .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2007, 56 (01) :125-143
[7]   Pain during topical photodynamic therapy of actinic keratoses with 5-aminolevulinic acid and red light source: randomized controlled trial [J].
Buinauskaite, Evelina ;
Zalinkevicius, Rimantas ;
Buinauskiene, Jurate ;
Valiukeviciene, Skaidra .
PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE, 2013, 29 (04) :173-181
[8]  
Callen JP, 1991, CANC SKIN, P27
[9]   Photodynamic therapy of actinic keratosis at varying fluence rates:: assessment of photobleaching, pain and primary clinical outcome [J].
Ericson, MB ;
Sandberg, C ;
Stenquist, B ;
Gudmundson, F ;
Karlsson, M ;
Ros, AM ;
Rosén, A ;
Larkö, O ;
Wennberg, AM ;
Rosdahl, I .
BRITISH JOURNAL OF DERMATOLOGY, 2004, 151 (06) :1204-1212
[10]   Photodynamic Therapy of Non-melanoma Skin Cancer with Methyl Aminolaevulinate is Associated with Less Pain than with Aminolaevulinic Acid [J].
Gaal, Magdolna ;
Otrosinka, Sylwia ;
Baltas, Eszter ;
Ocsai, Henriette ;
Olah, Judit ;
Kemeny, Lajos ;
Gyulai, Rolland .
ACTA DERMATO-VENEREOLOGICA, 2012, 92 (02) :173-175
12345