Antimicrobial properties of metal piperidine dithiocarbamate complexes against Staphylococcus aureus and Candida albicans

被引：14
|
作者：
Boadi, Nathaniel Owusu [1 ]
Degbevi, Mawuli [1 ]
Saah, Selina Ama [2 ]
Badu, Mercy [1 ]
Borquaye, Lawrence Sheringham [1 ,3 ]
Kortei, Nii Korley [4 ]
机构：
[1] Kwame Nkrumah Univ Sci & Technol, Dept Chem, Kumasi, Ghana
[2] Univ Energy & Nat Resources, Dept Chem Sci, Sunyani, Ghana
[3] Kwame Nkrumah Univ Sci & Technol, Cent Lab, Kumasi, Ghana
[4] Univ Hlth & Allied Sci, Sch Allied Hlth Sci, Dept Nutr & Dietet, PMB 31, Ho, Ghana
来源：
SCIENTIFIC AFRICAN | 2021年 / 12卷
关键词：
Piperidine dithiocarbamate ligand; Transition metal complexes; Antimicrobial properties; Staphylococcus aureus; Candida albicans; SINGLE-SOURCE PRECURSORS; ANTIFUNGAL ACTIVITY; DERIVATIVES; NICKEL(II); SULFIDE; SULFUR;
D O I：
10.1016/j.sciaf.2021.e00846
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
In this study, a series of metal piperidine dithiocarbamate complexes (M = Zn, Cu, Co, Fe, Ni, Bi and Ag) were synthesized and characterized using microelemental, (HNMR)-H-1, mass spectrometry and FT-IR analyses. Antimicrobial properties of the complexes were tested against Staphylococcus aureus and Candida albicans in a 96-well plate, using the broth dilution assay. The antimicrobial activity of the complexes was in the order Zn > Co > Cu > Ag= Bi = Ni > Fe against Staphylococcus aureus and Co > Zn > Fe > Ag= Bi = Cu = Ni against Candida albicans. The results indicate that the complexes were effective against the microorganisms at high concentrations. (C) 2021 The Author(s). Published by Elsevier B.V. on behalf of African Institute of Mathematical Sciences / Next Einstein Initiative.
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页数：8
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