Efficient and persistent gene transfer of AAV-CFTR in maxillary sinus

被引:170
作者
Wagner, JA
Reynolds, T
Moran, ML
Moss, RB
Wine, JJ
Flotte, TR
Gardner, P
机构
[1] Stanford Univ, Sch Med, Dept Mol Pharmacol, Stanford, CA 94305 USA
[2] Targeted Genet Corp, Seattle, WA USA
[3] Stanford Univ, Dept Med, Div Clin Pharmacol, Sch Med, Stanford, CA 94305 USA
[4] Stanford Univ, Sch Med, Dept Surg, Div Otolaryngol, Stanford, CA 94305 USA
[5] Stanford Univ, Sch Med, Dept Pediat, Div Allergy Pulm, Stanford, CA 94305 USA
[6] Stanford Univ, Dept Psychol, Cyst Fibrosis Res Lab, Stanford, CA 94305 USA
[7] Univ Florida, Dept Pediat, Gainesville, FL USA
[8] Univ Florida, Dept Mol Genet, Gainesville, FL USA
[9] Univ Florida, Dept Microbiol, Gainesville, FL USA
[10] Univ Florida, Gene Therapy Ctr, Gainesville, FL USA
关键词
D O I
10.1016/S0140-6736(05)77740-0
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:1702 / 1703
页数:2
相关论文
共 5 条
[1]  
Conrad CK, 1996, GENE THER, V3, P658
[2]   STABLE IN-VIVO EXPRESSION OF THE CYSTIC-FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR WITH AN ADENOASSOCIATED VIRUS VECTOR [J].
FLOTTE, TR ;
AFIONE, SA ;
CONRAD, C ;
MCGRATH, SA ;
SOLOW, R ;
OKA, H ;
ZEITLIN, PL ;
GUGGINO, WB ;
CARTER, BJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (22) :10613-10617
[3]  
MOSS RB, 1995, ARCH OTOLARYNGOL, V121, P566
[4]   A phase I/II study of tgAAV-CF for the treatment of chronic sinusitis in patients with cystic fibrosis [J].
Wagner, JA ;
Moran, ML ;
Messner, AH ;
Daifuku, R ;
Conrad, CK ;
Reynolds, T ;
Guggino, WB ;
Moss, RB ;
Carter, BJ ;
Wine, JJ ;
Flotte, TR ;
Gardner, P .
HUMAN GENE THERAPY, 1998, 9 (06) :889-909
[5]   METHOD FOR RAPID EVALUATION OF TOPICALLY APPLIED AGENTS TO CYSTIC-FIBROSIS AIRWAYS [J].
WINE, JJ ;
KING, VV ;
LEWISTON, NJ .
AMERICAN JOURNAL OF PHYSIOLOGY, 1991, 261 (02) :L218-L221