Chemical constitutes and anti-obesity potential of seedlings of purple-leafed rice in high-fat diet induced obese mice

被引:0
作者
Yang, Zenan [1 ]
Li, Xiaofang [2 ]
Li, Dianwei [1 ]
Wang, Cheng [1 ]
Song, Yuanqi [1 ]
Ren, Jingnan [2 ]
Li, Kaikai [2 ]
Chen, Hao [1 ]
机构
[1] Huazhong Agr Univ, Natl Key Lab Crop Genet Improvement, Wuhan 430070, Peoples R China
[2] Huazhong Agr Univ Wuhan, Coll Food Sci & Technol, Key Lab Environm Correlat Food Sci, Wuhan 430070, Peoples R China
关键词
ADIPOSE-TISSUE; BLACK RICE; ANTHOCYANINS; INFLAMMATION; ASSOCIATION; ADIPOKINES; BIOMARKERS; STAT3;
D O I
10.1039/d2fo02374a
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The seedlings of purple leafed rice (SPLR) are characterized by high contents of anthocyanins and various polyphenols, whose total anthocyanin content can reach 15.16 mg g(-1), indicating that SPLR may have many bioactivities. Therefore, in order to evaluate the anti-obesity potential value of SPLR, the nutrient components were first identified, and the anti-obesity effect of SPLR was evaluated with a high-fat diet (HFD) induced obese mouse model for 12 weeks. The results demonstrated that SPLR supplementation could alleviate HFD-induced obesity and suppress pro-inflammatory cytokine production and macrophage infiltration in epididymal white adipose tissue of HFD-induced obese mice. The findings indicated that supplementation with SPLR may contribute to preventing obesity and related complications.
引用
收藏
页码:12426 / 12435
页数:10
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