Multiclonal Origin of Macrolide-Resistant Mycoplasma pneumoniae Isolates as Determined by Multilocus Variable-Number Tandem-Repeat Analysis

被引:25
作者
Liu, Yang [1 ]
Ye, Xinye [1 ]
Zhang, Hong [2 ]
Xu, Xiaogang [1 ]
Wang, Minggui [1 ]
机构
[1] Fudan Univ, Huashan Hosp, Inst Antibiot, Shanghai 200433, Peoples R China
[2] Shanghai Jiao Tong Univ, Shanghai Childrens Hosp, Shanghai 200030, Peoples R China
基金
中国国家自然科学基金;
关键词
FIELD GEL-ELECTROPHORESIS; CHINA; STRAINS; SHANGHAI; PCR;
D O I
10.1128/JCM.00678-12
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
There was a high percentage of macrolide resistance in Mycoplasma pneumoniae clinical isolates in China. The genetic relatedness of macrolide-resistant M. pneunomiae strains was investigated using the multilocus variable-number tandem-repeat assay (MLVA). Among 152 M. pneunomiae isolates, the 137 macrolide-resistant strains were clustered into 15 MLVA types, indicating that the high macrolide resistance rate in M. pneumoniae is a result of the dissemination of the multiple resistant clones.
引用
收藏
页码:2793 / 2795
页数:3
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