Multiclonal Origin of Macrolide-Resistant Mycoplasma pneumoniae Isolates as Determined by Multilocus Variable-Number Tandem-Repeat Analysis

被引：25
|
作者：
Liu, Yang [1 ]
Ye, Xinye [1 ]
Zhang, Hong [2 ]
Xu, Xiaogang [1 ]
Wang, Minggui [1 ]
机构：
[1] Fudan Univ, Huashan Hosp, Inst Antibiot, Shanghai 200433, Peoples R China
[2] Shanghai Jiao Tong Univ, Shanghai Childrens Hosp, Shanghai 200030, Peoples R China
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2012年 / 50卷 / 08期
基金：
中国国家自然科学基金;
关键词：
FIELD GEL-ELECTROPHORESIS; CHINA; STRAINS; SHANGHAI; PCR;
D O I：
10.1128/JCM.00678-12
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
There was a high percentage of macrolide resistance in Mycoplasma pneumoniae clinical isolates in China. The genetic relatedness of macrolide-resistant M. pneunomiae strains was investigated using the multilocus variable-number tandem-repeat assay (MLVA). Among 152 M. pneunomiae isolates, the 137 macrolide-resistant strains were clustered into 15 MLVA types, indicating that the high macrolide resistance rate in M. pneumoniae is a result of the dissemination of the multiple resistant clones.
引用
收藏
页码：2793 / 2795
页数：3
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