The Role of T and B Cells in Atherosclerosis: Potential Clinical Implications

被引：0
作者：
Dumitriu, I. E. [1 ]
Kaski, J. C. [1 ]
机构：
[1] St Georges Univ London, Div Clin Sci, London SW17 0RE, England
来源：
CURRENT PHARMACEUTICAL DESIGN | 2011年 / 17卷 / 37期
关键词：
Adaptive immune response; T cells; B cells; atherosclerosis; LOW-DENSITY-LIPOPROTEIN; SYSTEMIC-LUPUS-ERYTHEMATOSUS; SMOOTH-MUSCLE CELLS; CORONARY-ARTERY-DISEASE; RECEPTOR-DEFICIENT MICE; HEAT-SHOCK PROTEIN-65; INTERFERON-GAMMA; NATURAL ANTIBODIES; OXIDIZED LDL; PNEUMOCOCCAL VACCINATION;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The chronic inflammation process that characterises atherosclerosis involves both the innate and adaptive arms of the immune system. Several lines of evidence have recently highlighted pivotal roles for T and B lymphocytes - cells that belong to the adaptive immune system - in the development and progression of atherosclerosis. In this review, we summarise the current knowledge on the roles of adaptive immune responses in atherosclerosis and present our views on how a better understanding of these immune mechanisms could shape future therapies to slow down or even prevent this disease.
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收藏
页码：4159 / 4171
页数：13
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