Organic Electrochemical Transistors Integrated in Flexible Microfluidic Systems and Used for Label-Free DNA Sensing

被引:283
|
作者
Lin, Peng [1 ,2 ]
Luo, Xiaoteng [3 ]
Hsing, I-Ming [3 ]
Yan, Feng [1 ,2 ]
机构
[1] Hong Kong Polytech Univ, Dept Appl Phys, Hong Kong, Hong Kong, Peoples R China
[2] Hong Kong Polytech Univ, Mat Res Ctr, Hong Kong, Hong Kong, Peoples R China
[3] Hong Kong Univ Sci & Technol, Dept Chem & Biomol Engn, Hong Kong, Hong Kong, Peoples R China
关键词
NUCLEIC-ACID; IMMOBILIZATION; HYBRIDIZATION; SURFACE; SENSOR; ARRAY;
D O I
10.1002/adma.201102017
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Organic electrochemical transistors are integrated in flexible microfluidic systems. A novel label-free DNA sensor is developed based on devices with single-stranded DNA probes immobilized on gate electrodes. These devices successfully detect complementary DNA targets at low concentrations using a pulse-enhanced hybridization technique in microfluidic channels. Organic electrochemical transistors are excellent candidates for flexible, highly sensitive, and low-cost biosensors.
引用
收藏
页码:4035 / +
页数:7
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