机构:
Univ Calif Santa Cruz, Sinsheimer Labs, Dept Mol Cell & Dev Biol, Ctr Mol Biol RNA, Santa Cruz, CA 95064 USAUniv Calif Santa Cruz, Sinsheimer Labs, Dept Mol Cell & Dev Biol, Ctr Mol Biol RNA, Santa Cruz, CA 95064 USA
Noller, HF
[1
]
机构:
[1] Univ Calif Santa Cruz, Sinsheimer Labs, Dept Mol Cell & Dev Biol, Ctr Mol Biol RNA, Santa Cruz, CA 95064 USA
The crystal structures of the ribosome and its subunits have increased the amount of information about RNA structure by about two orders of magnitude. This is leading to an understanding of the principles of RNA folding and of the molecular interactions that underlie the functional capabilities of the ribosome and other RNA systems. Nearly all of the possible types of RNA tertiary interactions have been found in ribosomal RNA. One of these, an abundant tertiary structural motif called the A-minor interaction, has been shown to participate in both aminoacyl-transfer RNA selection and in peptidyl transferase; it may also play an important role in the structural dynamics of the ribosome.
机构:
MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills RoadMRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road
Wimberly B.T.
Brodersen D.E.
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MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills RoadMRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road
Brodersen D.E.
Clemons Jr. W.M.
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MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road
Department of Biochemistry, Univ. of Utah School of Medicine, Salt Lake CityMRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road
Clemons Jr. W.M.
Morgan-Warren R.J.
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MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills RoadMRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road
Morgan-Warren R.J.
Carter A.P.
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MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills RoadMRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road
Carter A.P.
Vonrheln C.
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Global Phasing Ltd., Sheraton House, Cambridge CB3 0AX, Castle ParkMRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road
Vonrheln C.
Hartsch T.
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机构:
Göttingen Genomics Laboratory, Inst. F. Mikrobiologie und Genetik, Georg-August-Univ. Göttingen, D-37077 GöttingenMRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road
Hartsch T.
Ramakrishnan V.
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机构:
MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills RoadMRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road
机构:
MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills RoadMRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road
Wimberly B.T.
Brodersen D.E.
论文数: 0引用数: 0
h-index: 0
机构:
MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills RoadMRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road
Brodersen D.E.
Clemons Jr. W.M.
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h-index: 0
机构:
MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road
Department of Biochemistry, Univ. of Utah School of Medicine, Salt Lake CityMRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road
Clemons Jr. W.M.
Morgan-Warren R.J.
论文数: 0引用数: 0
h-index: 0
机构:
MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills RoadMRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road
Morgan-Warren R.J.
Carter A.P.
论文数: 0引用数: 0
h-index: 0
机构:
MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills RoadMRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road
Carter A.P.
Vonrheln C.
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h-index: 0
机构:
Global Phasing Ltd., Sheraton House, Cambridge CB3 0AX, Castle ParkMRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road
Vonrheln C.
Hartsch T.
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h-index: 0
机构:
Göttingen Genomics Laboratory, Inst. F. Mikrobiologie und Genetik, Georg-August-Univ. Göttingen, D-37077 GöttingenMRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road
Hartsch T.
Ramakrishnan V.
论文数: 0引用数: 0
h-index: 0
机构:
MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills RoadMRC Laboratory of Molecular Biology, Cambridge CB2 2QH, Hills Road