Candida auris: A Decade of Understanding of an Enigmatic Pathogenic Yeast

被引:54
作者
Kean, Ryan [1 ]
Brown, Jason [2 ]
Gulmez, Dolunay [2 ,3 ]
Ware, Alicia [1 ]
Ramage, Gordon [2 ]
机构
[1] Glasgow Caledonian Univ, Sch Hlth & Life Sci, Dept Biol & Biomed Sci, Glasgow G4 0BA, Lanark, Scotland
[2] Coll Med Vet & Life Sci, Sch Med Dent & Nursing, Glasgow G2 3JZ, Lanark, Scotland
[3] Hacettepe Univ, Med Microbiol Dept, Fac Med, Ankara 06230, Turkey
关键词
Candida auris; pathogenicity; in vivo models; biofilms; BIOFILM FORMATION; DROSOPHILA-MELANOGASTER; INFECTION; RECOGNITION; HAEMULONII; VIRULENCE; OUTBREAK; FUNGEMIA; GENOME; MODEL;
D O I
10.3390/jof6010030
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Candida auris is an enigmatic yeast that continues to stimulate interest within the mycology community due its rapid and simultaneous emergence of distinct clades. In the last decade, almost 400 manuscripts have contributed to our understanding of this pathogenic yeast. With dynamic epidemiology, elevated resistance levels and an indication of conserved and unique pathogenic traits, it is unsurprising that it continues to cause clinical concern. This mini-review aims to summarise some of the key attributes of this remarkable pathogenic yeast.
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页数:13
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