Helminth Microbiomes - A Hidden Treasure Trove?

被引：34

作者：

Jenkins, T. P. ^{[1
]}

Brindley, P. J. ^{[2
,3
]}

Gasser, R. B. ^{[4
]}

Cantacessi, C. ^{[1
]}

机构：

[1] Univ Cambridge, Dept Vet Med, Cambridge CB3 0ES, England

[2] George Washington Univ, Dept Microbiol Immunol & Trop Med, Washington, DC 20037 USA

[3] George Washington Univ, Res Ctr Neglected Dis Poverty, Sch Med & Hlth Sci, Washington, DC 20037 USA

[4] Univ Melbourne, Fac Vet & Agr Sci, Melbourne Vet Sch, Dept Vet Biosci, Parkville, Vic 3010, Australia

来源：

TRENDS IN PARASITOLOGY | 2019年 / 35卷 / 01期

基金：

英国惠康基金; 英国医学研究理事会; 英国生物技术与生命科学研究理事会; 澳大利亚研究理事会;

关键词：

WOLBACHIA ENDOSYMBIONTS; HOST; IMPACT; CONTAMINATION; PHOTORHABDUS; MICROFLORA; APOPTOSIS; PARASITE;

D O I：

10.1016/j.pt.2018.10.007

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

There is increasing attention on the complex interactions occurring between gastrointestinal parasitic helminths and the microbial flora (microbiota) inhabiting the host gut. However, little is known about the occurrence, structure, and function of microbial populations residing within parasite organs and tissues. In this article, we argue that an in-depth understanding of the interplay between parasites and their microbiomes may significantly enhance current knowledge of parasite biology and physiology, and may lead to the discovery of entirely novel, anthelmintic-independent interventions against parasites and parasitic diseases.

引用

页码：13 / 22

页数：10

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