'Phenytoin: Shepherd or Wolf in Disguise? Phenytoin-Induced Neurotoxicity: A Case Series

被引：4

作者：

Arora, Manali ^{[1
]}

Boruah, Deb K. ^{[2
]}

Thakker, Vishal ^{[1
]}

Bhanwra, Sangeeta ^{[3
]}

机构：

[1] Pramukhswami Med Coll, Dept Radiodiag, Anand, Gujarat, India

[2] Assam Med Coll, Dept Radiodiag, Dibrugarh, Assam, India

[3] Govt Med Coll, Dept Pharmacol, Amritsar, Punjab, India

来源：

NEUROLOGY INDIA | 2021年 / 69卷 / 04期

关键词：

Antiepileptic drugs; cerebellar degeneration; epilepsy; CEREBELLAR ATROPHY;

D O I：

10.4103/0028-3886.323888

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Phenytoin is a commonly used antiepileptic drug for various types of seizure disorders except for absent seizures. Long-term dose-dependent neurological side effects of phenytoin therapy include cerebellar atrophy, cerebral atrophy, and brain stem atrophy. Skull hyperostosis, gum hypertrophy, and megaloblastic anemia are other known effects of long-term therapy. We present four cases depicting clinical and neuroimaging findings of phenytoin-induced toxicity.

引用

页码：1014 / 1017

页数：4

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