The amount and distribution of precipitation play crucial roles in the occurrence of drought in the Weihe River Basin ( WRB), China. Using the precipitation data ( 1960-2010) of 21 meteorological stations, the spatial and temporal characteristics of short-, medium-, and long-term droughts on 3-, 6-, and 12-month time scales, respectively, were examined using the theory of runs and the Standardized Precipitation Index ( SPI). The trends of the drought characteristics were analyzed by a modified Mann-Kendall ( MMK) test method. Furthermore, comparative analysis of the SPI at different time scales was conducted. The results showed that ( 1) the main drought type was moderate drought, which occurred frequently in July and October; ( 2) the drought intensity and frequency were highest in the 1990s, and the drought severity and drought duration in the northwest was more serious than that in the east; ( 3) an increasing trend of short droughts appeared mainly in the spring and fall; an increasing trend of medium droughts mainly occurred in the 1990s and that of long-term droughts were mainly presented in the northwest region of the WRB; ( 4) SPI-3 can better reflect precipitation in the current month, SPI-6 has an advantage in characterizing drought persistence, and SPI-12 performs well in capturing extraordinary droughts; and ( 5) it was also observed that there is a strong relation between the precipitation distribution and drought zones in the basin, and the drought conditions changed continuously with the seasons depending upon the amount and spatial distribution of precipitation.