EPIC Early Detection of Ovarian Cancer

被引：6

作者：

Skates, Steven J. ^{[1
,2
]}

机构：

[1] Massachusetts Gen Hosp, Fruit St, Boston, MA 02114 USA

[2] Harvard Med Sch, Boston, MA USA

来源：

CLINICAL CANCER RESEARCH | 2016年 / 22卷 / 18期

关键词：

RANDOMIZED CONTROLLED-TRIAL; BIOMARKERS; MORTALITY; PROSTATE; RISK; LUNG;

D O I：

10.1158/1078-0432.CCR-16-1391

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

CA125 dominated performance for ovarian cancer early detection among four serum biomarkers evaluated in EPIC study prediagnostic serum, rising on average 3 years prior to detection. Adding HE4 provided only marginal improvement. This natural history supports annual testing for early detection and highlights the importance of biomarker discovery complementing CA125. (C) 2016 AACR.

引用

页码：4542 / 4544

页数：3

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