Daratumumab in light chain deposition disease: rapid and profound hematologic response preserves kidney function

被引:29
作者
Milani, Paolo [1 ,2 ]
Basset, Marco [1 ,2 ]
Curci, Paola [3 ]
Foli, Andrea [1 ,2 ]
Rizzi, Rita [3 ]
Nuvolone, Mario [1 ,2 ]
Guido, Raffaella [4 ]
Gesualdo, Loreto [4 ]
Specchia, Giorgina [3 ]
Merlini, Giampaolo [1 ,2 ]
Palladini, Giovanni [1 ,2 ]
机构
[1] Fdn Ist Ricovero & Cura Carattere Sci Policlin Sa, Amyloidosis Res & Treatment Ctr, Viale Golgi 19, I-27100 Pavia, Italy
[2] Univ Pavia, Dept Mol Med, Pavia, Italy
[3] Bari Hosp, Hematol Unit, Bari, Italy
[4] Bari Univ, Nephrol Unit, Bari, Italy
关键词
DEXAMETHASONE; AMYLOIDOSIS; SURVIVAL; BORTEZOMIB;
D O I
10.1182/bloodadvances.2020001553
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:1321 / 1324
页数:4
相关论文
共 24 条
  • [1] Daratumumab-based therapy in patients with heavily-pretreated AL amyloidosis
    Abeykoon, Jithma P.
    Zanwar, Saurabh
    Dispenzieri, Angela
    Gertz, Morie A.
    Leung, Nelson
    Kourelis, Taxiarchis
    Gonsalves, Wilson
    Muchtar, Eli
    Dingli, David
    Lacy, Martha Q.
    Hayman, Suzanne R.
    Buadi, Francis
    Warsame, Rahma
    Kyle, Robert A.
    Rajkumar, Vincent
    Kumar, Shaji
    Kapoor, Prashant
    [J]. LEUKEMIA, 2019, 33 (02) : 531 - 536
  • [2] Daratumumab plus pomalidomide and dexamethasone in relapsed and/or refractory multiple myeloma
    Chari, Ajai
    Suvannasankha, Attaya
    Fay, Joseph W.
    Arnulf, Bertrand
    Kaufman, Jonathan L.
    Ifthikharuddin, Jainulabdeen J.
    Weiss, Brendan M.
    Krishnan, Amrita
    Lentzsch, Suzanne
    Comenzo, Raymond
    Wang, Jianping
    Nottage, Kerri
    Chiu, Christopher
    Khokhar, Nushmia Z.
    Ahmadi, Tahamtan
    Lonial, Sagar
    [J]. BLOOD, 2017, 130 (08) : 974 - 981
  • [3] Bortezomib produces high hematological response rates with prolonged renal survival in monoclonal immunoglobulin deposition disease
    Cohen, Camille
    Royer, Bruno
    Javaugue, Vincent
    Szalat, Raphael
    El Karoui, Khalil
    Caulier, Alexis
    Knebelmann, Bertrand
    Jaccard, Arnaud
    Chevret, Sylvie
    Touchard, Guy
    Fermand, Jean-Paul
    Arnulf, Bertrand
    Bridoux, Frank
    [J]. KIDNEY INTERNATIONAL, 2015, 88 (05) : 1135 - 1143
  • [4] Daratumumab, Lenalidomide, and Dexamethasone for Multiple Myeloma
    Dimopoulos, M. A.
    Oriol, A.
    Nahi, H.
    San-Miguel, J.
    Bahlis, N. J.
    Usmani, S. Z.
    Rabin, N.
    Orlowski, R. Z.
    Komarnicki, M.
    Suzuki, K.
    Plesner, T.
    Yoon, S. -S.
    Ben Yehuda, D.
    Richardson, P. G.
    Goldschmidt, H.
    Reece, D.
    Lisby, S.
    Khokhar, N. Z.
    O'Rourke, L.
    Chiu, C.
    Qin, X.
    Guckert, M.
    Ahmadi, T.
    Moreau, P.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2016, 375 (14) : 1319 - 1331
  • [5] AL amyloidosis patients with low amyloidogenic free light chain levels at first diagnosis have an excellent prognosis
    Dittrich, Tobias
    Bochtler, Tilmann
    Kimmich, Christoph
    Becker, Natalia
    Jauch, Anna
    Goldschmidt, Hartmut
    Ho, Anthony D.
    Hegenbart, Ute
    Schoenland, Stefan O.
    [J]. BLOOD, 2017, 130 (05) : 632 - 642
  • [6] Monoclonal gammopathy of clinical significance: a novel concept with therapeutic implications
    Fermand, Jean-Paul
    Bridoux, Frank
    Dispenzieri, Angela
    Jaccard, Arnaud
    Kyle, Robert A.
    Leung, Nelson
    Merlini, Giampaolo
    [J]. BLOOD, 2018, 132 (14) : 1478 - 1485
  • [7] How I treat monoclonal gammopathy of renal significance (MGRS)
    Fermand, Jean-Paul
    Bridoux, Frank
    Kyle, Robert A.
    Kastritis, Efstathios
    Weiss, Brendan M.
    Cook, Mark A.
    Drayson, Mark T.
    Dispenzieri, Angela
    Leung, Nelson
    [J]. BLOOD, 2013, 122 (22) : 3583 - 3590
  • [8] Long-term reversibility of renal dysfunction associated to light chain deposition disease with bortezomib and dexamethasone and high dose therapy and autologous stem cell transplantation
    Gonzalez-Lopez, Tomas J.
    Vazquez, Lourdes
    Flores, Teresa
    San Miguel, Jesus Fernando
    Garcia-Sanz, Ramon
    [J]. CLINICS AND PRACTICE, 2011, 1 (04) : 205 - 208
  • [9] Daratumumab yields rapid and deep hematologic responses in patients with heavily pretreated AL amyloidosis
    Kaufman, Gregory P.
    Schrier, Stanley L.
    Lafayette, Richard A.
    Arai, Sally
    Witteles, Ronald M.
    Liedtke, Michaela
    [J]. BLOOD, 2017, 130 (07) : 900 - 902
  • [10] Lin J, 2001, J AM SOC NEPHROL, V12, P1482, DOI 10.1681/ASN.V1271482