Contraction,lnduced myokine production and release: Is skeletal muscle an endocrine organ.?

被引：271
作者：
Febbraio, MA
Pedersen, BK
机构：
[1] RMIT Univ, Cellular & Mol Metab Lab, Bundoora, Vic 3083, Australia
[2] Univ Copenhagen, Copenhagen Muscle Res Ctr, Copenhagen, Denmark
[3] Univ Copenhagen, Rigshosp, Dept Infect Dis, DK-2100 Copenhagen, Denmark
来源：
EXERCISE AND SPORT SCIENCES REVIEWS | 2005年 / 33卷 / 03期
关键词：
D O I：
10.1097/00003677-200507000-00003
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
The concentration of plasma interleukin-6 (IL-6) increases during physical exercise, but until recently the cellular origin of this increase has been unknown. Recent work has identified that skeletal muscle is a major source of this increase and the release of IL-6 from muscle can mediate metabolic processes. IL-6 is, therefore, the first identified "myokine" released from muscle that can now be termed an endocrine organ.
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页码：114 / 119
页数：6
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