Unprecedented stereoselective synthesis of cyclopenta[b]benzofuran derivatives and their characterisation assisted by aligned media NMR and 13C chemical shift ab initio predictions

被引：26

作者：

Riveira, Martin J. ^{[2
]}

Gayathri, Chakicherla ^{[1
]}

Navarro-Vazquez, Armando ^{[3
]}

Tsarevsky, Nicolay V. ^{[4
]}

Gil, Roberto R. ^{[1
]}

Mischne, Mirta P. ^{[2
]}

机构：

[1] Carnegie Mellon Univ, Dept Chem, Pittsburgh, PA 15213 USA

[2] Univ Nacl Rosario, Fac Ciencias Bioquim & Farmaceut, Inst Quim Rosario CONICET, RA-2000 Rosario, Santa Fe, Argentina

[3] Univ Vigo, Dept Quim Organ, Vigo 36310, Spain

[4] So Methodist Univ, Dept Chem, Dallas, TX 75275 USA

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2011年 / 9卷 / 09期

关键词：

RESIDUAL DIPOLAR COUPLINGS; SHIELDING CONSTANTS; ORGANIC-COMPOUNDS; RDCS; CONFIGURATION; ROCAGLAMIDE; ASSIGNMENT; MOLECULES; CHEMISTRY; ALIGNMENT;

D O I：

10.1039/c1ob05109a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new approach to the synthesis of cyclopenta[b]benzofuran derivatives via reaction of 1,3-dicarbonyl compounds with alpha, beta, gamma, delta-unsaturated aldehydes is described. The constitution and configuration of the new products have been firmly established by means of residual dipolar couplings (RDCs) and ab initio C-13 NMR chemical shift predictions.

引用

页码：3170 / 3175

页数：6

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