Autoimmune diseases and pregnancy

被引:20
作者
Tincani, Angela [1 ,2 ]
Nalli, Cecilia [1 ]
Khizroeva, Jamilya [3 ]
Bitsadze, Victoria [3 ]
Lojacono, Andrea [4 ]
Andreoli, Laura [1 ]
Shoenfeld, Yehuda [2 ,5 ,6 ]
Makatsariya, Alexander [3 ]
机构
[1] Univ Brescia, Dept Clin & Expt Sci, ASST Spedali Civili, Rheumatol & Immunol Unit, Brescia, Italy
[2] IM Sechenov First Moscow State Med Univ, Minist Hlth Russian Federat, Sechenov Univ, Moscow, Russia
[3] IM Sechenov First Moscow State Med Univ, Minist Hlth Russian Federat, Sechenov Univ, Dept Obstet & Gynecol, Moscow, Russia
[4] Univ Brescia, Dept Clin & Expt Sci, Obstet & Gynecol Unit, ASST Spedali Civili, Brescia, Italy
[5] Sheba Med Ctr, Zabludowicz Ctr Autoimmune Dis, Dept Med B, Ramat Gan, Israel
[6] Tel Aviv Univ, Sackler Fac Med, Tel Aviv, Israel
关键词
pregnancy; autoimmune diseases; systematic review; SYSTEMIC-LUPUS-ERYTHEMATOSUS; RHEUMATOID-ARTHRITIS; ANTIPHOSPHOLIPID SYNDROME; ANKYLOSING-SPONDYLITIS; CARDIAC MANIFESTATIONS; HELLP-SYNDROME; VASCULITIS; WOMEN; RISK; MANAGEMENT;
D O I
10.1016/j.beem.2019.101322
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Pregnancy in autoimmune diseases remains an argument of debate. In last years great improvements were done and with the correct medical support women with disease such as Systemic Lupus Erythematosus or Antiphospholipid Syndrome can afford a pregnancy and have healthy babies. The starting point is a good counselling. Women should be informed about risks that can occur taking some medications while pregnant and, on the other hand, that there are medications that can be safety assumed during pregnancy. Furthermore, there are known maternal risks factor such as the presence of antiphospholipid antibodies or anti-Ro/SSA antibodies that must be carefully manage by both rheumatologists and obstetrics. In addition, also disease activity during pregnancy can represent an issue. For all these reason, a multidisciplinary approach is mandatory in order to give our patients an optimal medical support, before, during and after pregnancy. (C) 2019 Published by Elsevier Ltd.
引用
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页数:14
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